白细胞计数及降钙素原与全身性感染的相关性分析

Study on relationship between white blood cell count and procalcitonin and sepsis

目的:确定全身性感染患者的传统炎性指标白细胞计数与降钙素原(PCT)的相关关系。方法:共有64例患者入选,临床发生全身性感染或全身性炎性反应综合征(SIRS)后24 h内测定血清PCT、IL-6同时记录白细胞计数。结果:PCT与血清IL-6水平密切相关。PCT对IL-6水平的预测能力强于白细胞计数。结论:与白细胞计数相比,PCT可以更准确地反映促炎性因子的升高情况,两者间比较差异无统计学意义(P>0.05)。

Objective To determine the correlations between predictive capability of conventional inflammatory marker white blood cell（WBC） count,and procalcitonin（PCT） with elevated levels of septic patients.Method Sixty-four patients were enrolled in the study.Serum concent rations of PCT,IL-6 were determined in 24 hours after clinical onset of sepsis or systemic inflammatory response syndrome.WBC count was also recorded.Results PCT was significantly correlated with serum IL-6 levels.The predictive capability was higher for PCT than WBC count.Conclusion Compared with white blood cell count,PCT may reflect the elevated levels of pro-inflammatory cytokines more reliably.