肝移植患者及正常人门静脉餐前、餐后血流动力学的对比研究

Color Doppler study of hepatic flow changes between liver transplantation and normal people before and after meal

目的:观测肝移植术后患者及正常人门静脉餐前、餐后血流动力学改变,探讨其相互关系及其临床意义。方法:应用彩色多普勒超声分别测量20例肝移植患者及20例正常人餐前、餐后门静脉血流参数,包括门静脉主干的直径(D),最大血流速度(Vmax),血流量(Q),探讨其相互关系。结果:肝移植术后患者及正常人餐前、餐后门静脉各血流参数比较,差异有统计学意义(P<0.05),表现为餐后各指标较餐前均有显著增加,肝移植患者与正常人比较,餐前、餐后血流速度、餐前、餐后血流量间比较,差异有统计学意义(P<0.05),表现为肝移植术后患者餐前、餐后门脉速度及血流量较正常患者均有显著增加,肝移植及正常餐前、餐后门脉内径间比较,差异无统计学意义(P>0.05)。结论:彩色多普勒对观测肝移植术后患者肝功能恢复情况提供参考,肝移植术后患者的门静脉内径、流速、流量等指标与正常组的差异,可能对理解肝血供是否异常有参考意义。

Objective To investigate the hemodynamic changes between the liver transplantation and normal people before and after glucose ingestion and to probe their relationships.Method Color Doppler sonography was applied to measure hemodynamic changes between liver transplantation and the normal people before and after glucoseingestion and to probe their relationships.Results The blood flow parameters of portal vein will be different after meal comparing to the state that had no food for normal person and the person taking liver transplantation operation（P0.05）.The value of blood flow parameter of portal vein when people had food was higher than that in case of people having no food.There was obvious difference in blood speed and blood flow rate between normal person and person taking liver transplantation in case of that the person had food and had no food（P0.05）.The value of blood speed and blood flow rate of the person taking liver transplantation operation were obvious higher than that of normal person.There was no obvious difference between liver transplantation person and normal person in the inner diameter of portal vein if they had no food.Conclusion CDFI can give us a clue in observing the recovering state of person who received liver transplantation operation.It is necessary for us to know if the liver blood supply is normal by using the difference in the ratio of the inner diameter,flow speed and flow rate related to portal vein,between liver transplantation person and normal person.