高精度热灌注系统治疗腹腔恶性肿瘤的应用研究

Application Research of High Precision Hyperthermic Perfusion Intraperitoneal System for Celiac Malignancy Treatment

目的:研究高精度"BR-TRG-II"型腹腔热灌注治疗系统的总体构成以及在腹腔恶性肿瘤热灌注化疗中的应用。方法:通过介绍该系统的构成,结合对39例典型腹腔假性黏液瘤患者的短期随访,对其治疗有效性和安全性进行评估。结果:该系统具有专业计算机热疗软件、全程动态控制等功能,临床初步应用结果表明,其各项性能完全能达到临床设计要求,尤其对腹膜假性黏液腺瘤治疗效果显著。结论:BR-TRC-II型腹腔热灌注治疗系统能满足临床腹腔热灌注化疗的需要,性能稳定,临床安全性好,在对患者生命指标、腹腔情况监测方面有待加强,同时通过改良,结合物理治疗,时于腹腔假性黏液腺瘤及类似腹腔广泛性肿瘤的治疗意义具有较广阔的临床应用前景。

Objective To study the overall system design principle of high-precision ＂BR-TRG-Ⅱ＂hyperthermic peritoneal perfusion treatment system and its application in abdominal malignant tumor thermal perfusion chemotherapy.Methods By the introduction of system structure,combined with the short-term follow-up of 39 cases with typical peritoneal pseudomyxoma peritonei,the treatment effectiveness and safety were evaluated.Results The system had a professional computer hyperthermia software and the whole dynamic control function,clinical preliminary application results showed that the BR -TRG-Ⅱperformance could fully meet the clinical design requirements,especially the treatment effect for pseudomyxoma peritonei adenoma was significant.Conclusion The BR-TRG-Ⅱsystem can meet the needs of clinical hyperthermic peritoneal perfusion chemotherapy,with stable performance and clinical safety.But the monitoring of patients＇ life indicators and abdominal situation should be strengthened.Through improvement and combination of physical treatment,the system has a broader clinical significance for abdominal pseudocyst mucinous adenoma and similar extensive abdominal tumor therapy.