摘要
目的通过观察淋巴瘤能谱CT参数特征,探讨能谱CT在淋巴瘤影像诊断方面的价值。方法采用GE能谱CT对22例初诊淋巴瘤患者[霍奇金病(HD)5例、非霍奇金淋巴瘤(NHL)17例]进行扫描,测量最大病灶的能谱曲线,记录40～140keV对应的CT值,观察同一病灶不同keV条件下CT值的变化规律。依据淋巴瘤部位、分期、病理类型、病灶大小、B症状、Ki-67等因素进行分组,比较不同组间淋巴瘤病灶在不同keV条件下CT值的差异。结果对于每个病灶的单能曲线,随着keV降低,曲线斜率逐渐变大,对应的CT值逐渐递增。在各临床病理因素中,仅病灶位置与单能CT值相关(P<0.05)。而对于14例胸部患者,HD的平均CT值在低能区段(40～70keV)与NHL比较,差异有统计学意义(P<0.05)。一般线性模型结果也显示,不同部位及病理类型淋巴瘤的单能CT值与低能keV存在相关关系。结论淋巴瘤能谱CT单能曲线具有相似的形态。不同部位淋巴瘤的单能CT值存在差异。同为胸部淋巴瘤,HD与NHL的单能CT值在低能量区段存在差异。
Objective To assess the characteristics of mono-energy CT in order to analyze its value in diagnosing lymphoma.Methods Twenty-two newly diagnosed patients（5 Hodgkin disease and 17 non-Hodgkin＇s lymphoma ） underwent dual energy CT examination.The mono-energy curves were assessed and CT values were determined according to different keV（40—140 keV）.The average CT values were compared between different groups classified by location,staging,histological type,size of lesion,B symptoms and Ki-67.Results CT values increased when the mono energy went lower.No correlation was found between other clinical factors and CT values except location.In 14 patients with thoracic lymphoma,the average CT values were significant different in patients with HD and NHL in lower keV（40—70 keV,P0.05）.Moreover,the results of general linear model showed that CT values of the lesions in different location and with different pathological types of lymphoma were related to lower keV.Conclusion CT values-mono energy curves of lymphoma are similar.The mono-energy CT values with location of lesions and pathology type of lymphoma show differences in lower keV in patients with lymphoma.
出处
《中国医学影像技术》
CSCD
北大核心
2012年第5期1001-1005,共5页
Chinese Journal of Medical Imaging Technology
