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骨巨细胞瘤生物学特性研究进展 被引量：3

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摘要 骨巨细胞瘤临床上较为常见。其虽为良性肿瘤，却于局部侵袭生长，且可远隔转移，目前治疗效果尚不理想^[1]。改善当前治疗困境，有赖于更为深入地了解其生物学特性，我们将就近年来相关研究的现况进行综述。一。
作者 兰杰 刘晓光 韦峰 姜亮 刘忠军
机构地区 北京大学第三医院骨科
出处 《中华外科杂志》 CAS CSCD 北大核心 2012年第5期468-470,共3页 Chinese Journal of Surgery
关键词 骨巨细胞瘤 生物学特性 治疗效果 良性肿瘤 基质细胞 肿瘤细胞
分类号 R738.1 [医药卫生—肿瘤]
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参考文献35

  • 1本刊编辑部,杨子明,郭卫,牛晓辉,黄啸原.骨巨细胞瘤生物学特性及治疗对策高级学术论坛学术讨论纪要[J].中华外科杂志,2006,44(12):793-796. 被引量：9
  • 2Ghert M, Simunovic N, Cowan RW, et al. Properties of the stromal cell in giant cell tumor of bone. Clin Orthop Relat Res, 2007, 459: 8-13.
  • 3Wulling M, Delling G, Kaiser E. The origin of the neoplastic stromal cell in giant cell tumor of bone. Hum Pathol, 2003, 34 : 983-993.
  • 4Nishimura M, Yuasa K, Mori K, et al. Cytological properties of stromal cells derived from giant cell tumor of bone (GCTSC) which can induce osteoclast formation of human blood monocytes without cell to cell contact. J Orthop Res, 2005, 23: 979-987.
  • 5Gorunova L, Vult van Steyern F, Storlazzi CT, et al. Cytogenetic analysis of 101 giant cell tumors of bone: nonrandom patterns of telomeric associations and other structural aberrations. Genes Chromosomes Cancer, 2009, 48 : 583-602.
  • 6Gebre-Medhin S, Broberg K, Jonson T, et al. Telomeric associations correlate with telomere length reduction and clonal chromosome aberrations in giant cell tumor of bone. Cytogenet Genome Res, 2009, 124 : 121-127.
  • 7Moskovszky L, Szuhai K, Krenacs T, et al. Genomic instability in giant cell tumor of bone. A study of 52 cases using DNA ploidy, relocalization FISH, and array-CGH analysis. Genes Chromosomes Cancer, 2009, 48: 468-479.
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  • 9Papanastassiou I, Ioannou M, Papagelopoulos PJ, et al. P53 expression as a prognostic marker in giant cell tumor of bone: a pilot study. Orthopedics, 2010, 33:307.
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共引文献8

同被引文献18

  • 1毕乃贵,王民,王莹.CD147在骨巨细胞瘤中的表达及临床意义[J].现代肿瘤医学,2007,15(12):1846-1848. 被引量：7
  • 2Niu X, Zhang Q, Hao L, et al. Giant cell tumor of the extremity : retrospective analysis of 621 Chinese patients from one institution [J:. J Bone Joint Surg Am, 2012, 94(5) :461-467.
  • 3Klenke FM, Wenger DE, Inwards CY, et al. Giant cell tumor of bone: risk factors for recurrence [ J :. Clin Orthop Relat Res, 2011, 269(2) : 591-599.
  • 4Lan J, Liu X, Rong W, et al. Stro-l(+) stromal cells have stem-like features in giant cell tumor of bone [ J ]. J Surg Oncol, 2012, 106(7) :826-836.
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  • 6Weigmann A, Corbeil D, Hetlwig A, et al. Prominin-1, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of nonepithelial cells [ J ]. Proc Nat1 Acad Sci USA, 1997, 94 (23) : 12425-12430.
  • 7Grosse-Gehling PI, Fargeas CA, Ditffeld C, et al. CD133 as a biomarker for putative cancer stem cells in solid tumours: limita- tions, problems and challenges[ Jl. J Pathol,2013, 229(3) :355 -378.
  • 8Oliveira VC, van der Heijden L, van der Geest IC, Giant cell tumours of the small bones of the hands and feet: long-term results of 30 patients and a systematic literature review[ J]. Bone Joint J,2013, 95(6) :838-845.
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  • 10Errani C, Ruggieri P, Asenzio MA, et al. Giant cell tumor of the extremity : A review of 349 cases from a single institution [ J 1. Cancer Treat Rev,2010, 36(1) :1-7.

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中华外科杂志
2012年 第5期

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