大脑皮层静脉血栓的临床诊断及分析

Clinical diagnosis and analysis of cerebral cortical veinous thrombosis

目的 探讨大脑皮层静脉血栓的临床、影像学特点，以便早期诊断、及时治疗。方法收集2010年首都医科大学宣武医院诊治的皮层静脉血栓患者，对其临床及影像学资料进行回顾性分析。结果 共收集4例皮层静脉血栓患者，平均年龄40岁。临床症状主要表现为不同程度的头痛、局灶性神经系统体征，CT、MRI表现为一侧或双侧、单发或多发的出血或梗死改变。其中1例出血，1例梗死，2例梗死伴出血。 结论 头痛、局灶性神经系统体征是大脑皮层静脉血栓的常见症状，CT、MRI是辅助诊断大脑皮层静脉血栓较为有效的方法。

Objective To investigate the clinical and radiological characteristics of cortical vein thrombosis for early diagnosis and treatment. Methods Retrospective analysis was carried out with the clinical cases of cortical vein thrombosis in 2010. The symptoms, sign, neuroimaging were analyzed and related literatures were reviewed. Results Four patients were collected, average age was forty years old. The main symptoms were headache and focal neurological signs in varying degrees, infarction or hemorrhage in one or two sides of parietal lobe could be found in CT or MRI. Hemorrhage was found in two patients, infarction was found in one patient, hemorrhage and infarction were both found in another patient. Conclusions Headache and focal neurological signs are the common sings and symptoms of patients with cortical vein thrombosis. CT and MRI are effective methods for the diagnosis of cortical vein thrombosis.