瘦素与肿瘤坏死因子检测在结核性与恶性胸腔积液中的诊断价值

目的 探讨瘦素与肿瘤坏死因子检测在结核性与恶性胸腔积液中的诊断价值。方法 选择2006年1月～2011年10月本院入院治疗的45例胸腔积液患者,比较良恶性胸腔积液患者中LEP及TNF-α水平。结果 结核性胸腔积液组LEP及TNF-α低于恶性胸腔积液组,两组比较差异均有统计学意义(均P<0.05)。结论 瘦素与肿瘤坏死因子检测在结核性与恶性胸腔积液中有重要的的诊断价值。

Objective To investigate the value of leptin （LEP） and tumor necrosis factor-α （TNF-α） in the diagnosis of tuberculous and malignant pleural effusion. Methods 45 cases pleural effusion patients were chosen in our hospital from January 2006 to October 2011, LEP and TNF-α in tuberculous and malignant pleural effusion patients were tested and compared. Results LEP and TNF-α in tuberculous pleural effusion group were lower than those of malignant pleural effusion group, there were statistically significant between two groups （P 〈 0.05）. Conclusion The levels of LEP and TNF-α in malignant pleural effusion are high, there is high value of leptin and tumor necrosis factor-a in the diagnosis of tuberculous and malignant pleural effusion.