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复发性外阴癌的处理 被引量:3

Treatment for recurrent vulvar cancer
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摘要 复发性外阴癌目前没有标准治疗。小样本回顾性资料显示:孤立性肿块手术切除预后好,手术尽量做到无残留病灶,有残留病灶者术后辅助放化疗可能有效;区域性或远处转移患者预后差,可以选择放化疗;化疗作用有限,需要集中病例进行前瞻性临床研究确定最佳治疗方案。 there is no standard treatment. Some small retrospective studies show that recurrent patients with an isolated tumor receive complete surgery would have better survival, and surgery should be no residual, adjuvant radio-chemotherapy may have some effectiveness for those with residual disease; for patients with a regional and/or distant recurrence, radio-chemotherapy may be helpful, but the response rate is low. Chemotherapy has shown minimal activity. There is a need to gather patients in central institutions to take prospective clinical trials to identify the best therapeutic approaches for recurrent vulva cancers.
作者 李子庭
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2012年第5期344-348,共5页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 外阴癌 肿瘤复发 化疗 放疗 vulva cancer tumor recurrence chemotherapy radiotherapy
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  • 1Monaghan JM. The management of carcinoma of the vulva [ A ]. Sheperd JH, Monaghan JM, editors. Clinical gynaecological on- cology[M]. 2nd ed. Oxford: Blackwell Scientific Publications, 1990 : 140-167.
  • 2Stang A, Streller B, Eisinger B, et al. Population-based inci- dence rates of malignant melanoma of the vulva in germany [ J ]. Gynecol Onco1,2005,96:216-221.
  • 3Maggino T, Landoni F, Sartori E, et al. Patterns of recurrence in patients with squamous cell carcinoma of the vulva: a multi- center CTF study [ J ]. Cancer, 2000,89 : 116-122.
  • 4Trope C, Johnsson JE, Larsson G, et al. Bleomycin alone or combined with mitomycin C in treatment of advanced or recurrent squamous cell carcinoma of the vulva [ J ]. Cancer Treat Rep, 1980,64: 639-642.
  • 5Witteveen PO,van der Velden J, Vergote I , et al. Phase Ⅱ study on paclitaxel in patients with recurrent, metastatic or local- ly advanced vulvar cancer not amenable to surgery or radiothera- py: a study of the EORTC-GCG (European Organisation for Re- search and Treatment of Cancer Gynaecological Cancer Group ) [J]. Ann Oncol, 2009,20(9):1511-1516.
  • 6Thigpen JT, Blesing JA, Homesley HD, et al. Phase Ⅱtrials of cisplatin and pierazinedione in advanced or recurrent squamous cell carcinoma of the vulva : a Gynecologic Oncology Group study [ J]. Gynecol Oncol, 1986,23 : 358-363.
  • 7Scheistroen M, Trope C. Combined bleomyein and irradiation in preoperative treatment of advanced squamous cell carcinoma of the vulva[ J]. Acta Oncol, 1993,32:657-661.
  • 8Landoni F, Maneo A, Zanetta G, et al. Concurrent preoperative chemotherapy with 5-fluorouracil and mitomycin C and radiother- apy (FUMIR) followed by limited surgery in locally advanced and recurrent vulvar carcinoma [ J ]. Gynecol Oncol, 1996,61 : 321-327.
  • 9Russell AH, Mesic JB, Scudder SA, et al. Synchronous radia- tion and cytotoxic chemotherapy for locally advanced or recurrent squamous cancer of the vulva[ J]. Gynecol Oncol, 1992,47:14- 20.
  • 10Dun'ant KR, Mangioni C, Lacave A J, et al. Bleomycin, metho- trexate and CCNU in advanced inoperable squamous cell carci- noma of the vulva : a phase Ⅱstudy of the EORTC gynaecological cancer cooperative group (GCCG) [ J]. Gynecol Oncol, 1990, 37 : 359-362.

同被引文献38

  • 1李强,汤春生.外阴癌的化学治疗[J].中国实用妇科与产科杂志,2004,20(11):643-645. 被引量:3
  • 2Siegel R,Naishadham D,Jemal A. Cancer statistics[J]. CA Cancer J Clin, 2012,62(1) : 10-29.
  • 3Rauh-Hain J, Clemmer J, Clark R, et al. Management and outcomes for elderly women with vulvar cancer over time [J]. BJOG,2014,121(6):719-727.
  • 4Chhabra S,Bhavani M,Deshpande A. Trends of vulvar cancer[J]. Obstet Gynecol,2014,34(2) : 165-168.
  • 5Deppe G,Mert L,Winer IS. Management of squamous cell vulvar eancer:a review [J]. J Obstet Gyneacol Res, 2014,40(5) 1217-1225.
  • 6Gunther V, Malchow B, Schubert M, et al. Impact of radi- cal operative treatment on the quality of life in women with vulvar cancer---a retrospective study [J]. Eur J Surg Oncol, 2014,40(7) : 875 -882.
  • 7孙建衡,票树模,商永良.妇科肿爝学[M].第2版.北京:北京大学医学出版社,2011.394-413.
  • 8Cormio G,Loizzi V,Gissi F,et al. Cisplatin and vinorel- bine chemotherapy in recurrent vulvar carcinoma [J]. On- cology, 2009,77(5) : 281-284.
  • 9Neville F. Vular cancer[A]jonathan S, Neville F. Berek & Hacker's gynecologic oncology[M]. 2nd ed. Philadelphia: lAppineott Williams & Wilking,2010.536-592.
  • 10John W, Kunos C,Edward J, et al. Vulva [A]. Richard R, Berchuck A, Markman M, et al. Principles and practice of gynecologic oneology [M]. 6th ed. Philadelphia:Lippincott Williams & Wilking,2013.523-556.

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