介入治疗原发性肝癌的临床疗效分析

Clinical analysis of interventional procedure in primary hepatic cancer

目的比较肝动脉化疗栓塞术(TACE)、微波消融治疗(PMCT)及TACE+PMCT 3种介入治疗方案对原发性肝癌的临床疗效,为制定治疗方案,提高原发性肝癌(PHC)的治疗疗效提供依据。方法回顾性分析107例分别进行TACE、PMCT及TACE+PMCT 3种介入治疗方案治疗的原发性肝癌病例的临床疗效。结果 3组中以TACE+PMCT治疗效果最好,生存率最高,血清甲胎蛋白(AFP)改善以及肝功能分级改善情况以TACE+PMCT组最佳。结论TACE+PMCT疗效显著,治疗后AFP及肝功能改善情况显著优于单纯TACE或PMCT方案,是治疗原发性肝癌的疗效确切、安全、微创的综合治疗方法。

Objective To provide a theory-based evidence for the formulation of treatment plan,the effects of inter-ventional treatment by comparing interventional treatments transcatheter arterial chembolization（TACE）,percutanousn microwave coagulation therapy（PMCT） and TACE＋PMCT for primary hepatic cancer（PHC）.Methods One hundred and seven PHC patients treated with TACE,PMCT and TACE＋PMCT were studied retrospectively.Results Of the 3 groups,TACE＋PMCT group obtained the best curative effect,the highest survival rate,the best achievement on reducing AFP value and the improvement of liver functional also happened in TACE＋PMCT group.Conclusion TACE＋PMCT treament has notably curative effect.With TACE＋PMCT treatment,the decrease of AFP value after treatment and the improvement of liver function on paients are also obviously better than treated with either TACE or PMCT,It is a safe and effective method in the treatment of PHC with few complication.