慢性疲劳综合征病人的疲劳、抑郁、焦虑与生活事件的特点及其相关性分析

A study on the characteristic of fatigue,depression,anxiety,life event and their correlation in the patients with chronic fatigue syndrome

目的 分析慢性疲劳综合征 (简称 CFS)病人的疲劳、抑郁、焦虑及生活事件的特点 ,并探讨其间相关性。方法 运用量表的形式 ,观察了 130例 CFS病人及 6 5例年龄、性别均相匹配的健康对照者的疲劳、抑郁、焦虑及生活事件状况。结果 1CFS病人存在明显的脑力与躯体疲劳 ,其特点是 :存在明显的由于疲劳而出现的心理后果 ;疲劳具有明显的情境特异性 ;对于休息、睡眠的反应不明显。 2 CFS病人具有明显的抑郁与焦虑的情绪改变。 3CFS病人发病前的负性事件值显著高于正常对照组 ,主要表现在家庭生活及工作学习方面。 4CFS的疲劳总分、焦虑分值、抑郁指数、生活事件分值 (主要是负性事件 )之间呈正相关。结论 CFS病人疲劳、抑郁、焦虑的严重程度与发病前的生活事件刺激量有密切的关系 ,病人的情绪改变受疲劳程度的影响。

Objective To reasearch the characteristic of fatigue,depression,anxiety,life events and their correlation in the patients with chronic fatigue syndrome(CFS).Method By use of some scales, to observe fatigue,depression,anxiety and life events of 130 CFS patients and 65 health control subjects matched with the patients in age and gender.Results 1.Compared with control subjects, CFS patients had signficant mental and physical fatigue,with different characteristic from the controls;significant depression and anxiety;more negative life events,especially on the aspects of family,work and study.2.Positive correlation was shown among the total fatigue value,the degree of anxiety and depression and the stimulation quantities of life events(especially negative events). Conclusion The degree of fatigue ,depression and anxiety of CFS patients had close relationship with the stimulation quantities of life events,in addition,the degree of fatigue had influence on the changes of such emotions as anxiety and depression.