不同亚型功能性消化不良并发抑郁、焦虑症状情况及对患者生活质量的影响

Analysis of Anxious,Depression in Different Subtypes of Functional Dyspepsia and Their Effect on the Qulity of Life

目的观察功能性消化不良(functional dyspepsia,FD)的3种亚型餐后不适综合征(postprandial distress syndrome,PDS)和上腹疼痛综合征(epigastric painsyndrome,EPS)以及PDS重叠EPS患者的抑郁、焦虑症状情况及对生活质量(qualityoflife,QOL)的影响。方法 144例FD患者分成3组,采用综合医院焦虑,抑郁量表(hospital anxiety and depressive scale,HADS)及SF-36评分。结果 PDS组抑郁、焦虑及抑郁合并焦虑的患病率为18.75%、29.17%、4.17%,EPS组为8.33%、14.58%、2.08%,EPS合并PDS组为27.08%、45.83%,10.42%;3组SF-36评分有极显著性差异(P<0.01)。结论不同亚型FD有不同的精神心理因素影响,PDS与PDS重叠EPS患者抑郁、焦虑症状及生活质量影响比EPS患者严重,特别是焦虑,尤以PDS重叠EPS者为甚。

Objective To investigate the role of depression and anxiety symptoms on the quality of life in different subtypes functional dyspepsia（FD）：postprandial distress syndrome（PDS）,epigastric pain syndrome（EPS） and PDS overlapping EPS.Methods 144 patients with FD were divided into three groups.The hospital anxiety and depressive scale（HADS） and qual：ty of life quality of life（QOL）in the three groups were analyzed.Results The rate of patients who had depressive symptom or/and anxiety symptom in all PDS patients was 18.75%,29.17%,4.17%,and in all EPS patients was 8.33%,14.58%,2.08%,and in all EPS overlapping PDS patients was 27.08%,45.83%,10.42%.There was significant difference in SF-36 among the three groups（P0.01）.Conclusion There were different pathogenesist in the different subtypes of FD,but the symtomps of anxiety and depression and QOL are more severe in the PDS and PDS overlapping EPS group than the EPS group,especially the anxious in PDS overlapping EPS.