有创-无创序贯通气治疗在AECOPD撤机患者中的应用

The Application of Sequential Invasive-noninvasive Mechanical Ventilation on Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

目的研究有创-无创序贯通气在AECOPD患者撤机中的应用和时机。方法随机将26例AECOPD患者分为有创-无创序贯通气治疗组A和常规有创通气治疗组B,A组由有创通气过渡到无创通气后撤机拔管,B组则有创通气直至撤机拔管。结果两组机械通气时间、脱机成功率、呼吸机相关性肺炎发生率、住院时间均有明显差异(P<0.01)。结论采用有创-无创序贯通气可以提高AECOPD患者撤机成功率。

Objective To evaluate the effectiveness and the optimal time for extubation and sequential noninvasive ventilation（NIV） in patients with acute exacerbation of chronic obstructive pulmonary disease（AECOPD） who received invasive ventilation.Method 26 patients with AECOPD who received endotracheal invasive ventilation were randomly assigned to receive NIV immediately after extubation（A group） and to continue invasive ventilation（B group） at the time AECOPD control window had appeared.Results Duration of mechanical ventilation,success ratio of offline,the incidence of ventilator associated pneumonia,hospital stays were statistically difference（P0.01）.Conclusions Using sequential invasive-noninvasive mechanical ventilation could increase success ratio in weaning mechanical ventilation.