参麦注射液对非小细胞肺癌化疗减毒作用的观察

Observation on Attenuation of Shenmai Injection for Chemotherapy of Non-small Cell Lung Cancer

进一步探讨参麦注射液对化疗的减毒作用。方法 :对肺癌患者 2 0 3例进行回顾性分析。结果 :化疗后 OKT1值参麦组略上升 ,对照组下降 ( P<0 .0 5) ;OKT4 / OKT8比值治疗后参麦组明显高于对照组 ( P<0 .0 5)。参麦组 s IL - 2受体水平下降 ( P<0 .0 5) ,LAK细胞、NK细胞略上升( P<0 .0 5) ,对照组 s IL - 2受体水平下降不明显 ( P<0 .0 5) ,L AK细胞、NK细胞均下降 ( P <0 .0 5) ;化疗后参麦组外周血白细胞和血小板降低程度明显小于对照组 ( P<0 .0 5) ,全身体力状况也优于对照组。结论 :参麦液对化疗有一定的减毒作用 ,使化疗计划更易于完成。

To observe the attenuation of Shenmai injection on chemotherapy of non-small cell lung cancer (NSCLC).Methods:203 cases with advanced NSCLC were statistically analysed based on a retrospective study.Results:The results showed that after chemotherapy the level of OKT 1 and OKT 4/OKT 8 were increased in Shenmai group when compared with the control group (P< 0.05).The level of sIL-2 receptor was lowered and level of LAK or NK increased significantly in Shenmai group (P<0.05),while the level of sIL-2 receptor in the control group was not lowered (P> 0.05) but the level of LAK or NK was lowered significantly in control group (P< 0.05). Conclusions:Shenmai injection was of attenuation on chemotherapy,which could facilitate the chemotherapy.