摘要
目的:通过探讨不同级别少突胶质细胞瘤的影像学特点并与病理表现对照,为少突胶质细胞瘤的临床治疗提供帮助。方法:回顾性分析57例经病理证实的不同级别少突胶质细胞瘤的影像表现,并和病理作对照。结果:少突胶质细胞瘤(WHOⅡ级)35例,中位年龄34岁,好发于额、顶叶皮髓质交界区,边界模糊,29例CT呈稍低密度,6例CT呈混杂密度,31例T1WI呈低信号,4例呈等信号,35例T2WI呈高信号,增强扫描32例呈轻度强化,3例呈不均匀强化,32例伴钙化,7例囊变,8例出血,5例伴瘤周水肿;间变少突胶质细胞瘤(WHOⅢ级)22例,中位年龄32岁,好发于额、顶、颞皮髓质交界区,边界较清,10例CT呈稍低密度,12例CT呈混杂密度,19例T1WI例呈低信号,3例呈等信号,19例T2WI呈高信号,增强扫描2例轻度强化,20例呈明显强化,3例伴钙化,12例囊变坏死,9例出血,22例伴瘤周水肿。结论:间变型少突胶质细胞瘤(WHOⅢ级)在囊变坏死、出血、瘤周水肿及强化形式方面较少突胶质细胞瘤更加明显,这些影像学特征有助于对该类肿瘤术前分级的诊断,为肿瘤的临床治疗提供帮助。
Objective: To explore the imaging features of different grades of oligodendrogliomas and pathological results for guidance of treatment.Methods: Imaging findings of 57 oligodenodrogliomas of different grades confirmed by pathology were retrospectively analyzed.Results: Thirty-five patients were grade Ⅱ oligodendrogliomas(WHO Ⅱ grade),with a median age of 34 years.Most of the tumors occurred in the cortical and medullary junction of parietal and frontal lobes,with ill defined boundary.29 cases were slightly low density and 6 cases were mixed density on CT.On T1WI,31 cases showed low signal and 4 showed equal signal.On T2WI,35 cases showed high signal.Enhanced CT scan showed mild enhancement in 32 cases and heterogeneous enhancement in 3 cases.Thirty-two cases had calcification;7 cases had cystic degeneration;8 cases had bleeding and 5 cases had peritumoral edema.Anaplastic oligodendrogliomas(WHO Ⅲ grade) were found in 22 cases with a median age of 32 years.Most of the tumors occurred in cortex and medulla junction of frontal,parietal and temporal lobes,with clear boundary.On CT images,10 cases was slightly low-density,12 cases were mixed density.On T1WI,19 cases were low signal and 3 cases were iso-intense.19 patients showed high signal on T2WI.On enhanced CT scan,2 cases showed mild enhancement and 20 cases showed significant enhancement.3 cases had calcification;12 cases had cystic necrosis;nine cases had hemorrhage and 22 cases had peritumoral edema.Conclusions: Cystic necrosis,hemorrhage,edema and enhancement were more common in anaplastic oligodendrogliomas(WHO Ⅲ grade) than in glioblastoma.These imaging features contribute to tumor classification before surgery,and treatment planning for the tumor.
出处
《中国临床医学影像杂志》
CAS
2012年第5期305-308,315,共5页
Journal of China Clinic Medical Imaging