病毒性肝炎患者AAT及PAB血清水平变化

The change of serum AAT and PAB level in patients with viral hepatitis

目的 :研究病毒性肝炎患者血清 AAT,PAB水平变化的临床意义。方法 :采用 COBASEMIRA生化分析仪检测 94例病毒性肝炎患者血清标本。结果 :13例 A H组、 45例 CH组、2 8例 L C组、 8例 FH组 A AT,PAB水平均显著低于正常对照组 ( P <0 .0 1) ,FH组与 AH组、 CH组、 L C组比较 A AT,PAB水平下降有显著性差异 ( P<0 .0 5 )。且 AAT与 PAB水平呈正相关 ( r=0 .2 85 ,P<0 .0 1)。结论 :AAT及 PAB血清水平下降与病毒性肝炎患者肝脏病变严重程度有关 ,PAB可作为反映肝脏功能的灵敏指标。

Objective: The aim of the study is to observe the clinical significance of serum AAT and PAB level in patients with viral hepatitis. Methods: By COBASEMIRA physiochemmical analysis instrument, 94 cases serum samples in patients with viral hepatitis were examined. Results: Serum AAT and PAB level in group AH, group CH, group LC and group FH respectively was noted lower than those in normal control group (P<0.01), and serum AAT and PAB level in group FH was noted decrease as compared with those in group AH, group CH and group LC respectively. Besides, the level between AAT and PAB appeared positive correlation.Conclusion: There was correlation between the decrease in serum AAT, PAB level and the severe liver diseases in patients with viral hepatitis, which also showed that PAB could serve as a sensitive parameter for hepatic function.\;