子宫内膜与细菌 L 型感染

Bacterial L-form Infection of Endometria

本文报道41例宫腔刮出物的病原微生物培养,其中子宫异常出血和早孕胎盘组织各15例,月经紊乱6例和不孕症5例。19例细菌培养为阳性(46.35),19例中之7例为细菌兼有 L 型感染,8例为单纯 L 型感染,3例为解脲脲原体和1例 G^+厌氧球菌感染。L 型菌落呈典型“油煎蛋”样或颗粒样。子宫内膜和胎盘组织切片的细菌学检查发现大量 L 型巨形体、圆球体和长丝体。作者认为在妇产科范围内,细菌 L 型和解脲脲原体感染并非少见,可能是子宫异常出血、月经紊乱、不孕症和流产的重要原因之一。L 型的形成与抗生素治疗及体内因素的诱导有关。在治疗 L 型感染过程中,药物的选择很重要。

In this article 41 specimens taken from intrauterine curettage were used for isolation of pathogenic organisms,15 specimens from patients with abnormal bleeding,1,5 from pregnancy in the first trimester,6 from cases with menstrual disorder and 5 from women with sterility.The cultures appeared to be associated with both bacteria and L-forms,8 with L-forms only,1 with Gram positive anacrobic cocci and 3 with ureaplasma.The colonies of L-forms had an appearance of “fried egg”or in granular forms.In histolo- gical sections,large bodies,spherical bodies, long filaments of L-forms were disclosed.It showed that L-forms and ureaplasma infecti- ons are not rare in the fields of gynecology and obstetrics.They are probably important causes of abnormal bleedings,menstrual di- sorder,sterility and abortion.The occurrence of L-forms is supposed to be due to the influ- ence of antibiotics used for treatment or some intrincic factors of the human body.The selection of drus for treatment is,therefore, very important in the cnre of diseases.