摘要
目的 比较RPR法和TPPA法对梅毒的检测结果 ,同时了解本地区近几年来梅毒的发病情况。方法 应用RPR法与TPPA法对衡阳地区近 4年来拟诊为STD患者的血清进行梅毒初筛和确诊试验 ,4年梅毒检出率用趋势性x2 检验。结果 本地区STD患者中梅毒的检出率呈逐年上升的趋势 (x2 =15.0 70 ,P <0 .0 1)。对一期、二期梅毒 ,RPR和TPPA法显示出良好的一致性 ;但对潜伏期梅毒 ,RPR法可能出现假阴性、假阳性。结论 对一、二期梅毒 ,RPR可替代TPPA法 ;而在其它情况下 ,TPPA优于RPR法。TPPA法可定量检测梅毒特异性抗体 ,应作为临床梅毒确诊的检测手段。
Objective: To compare the result of syphilis detected by RPR with that by TPPA and to acquire the information about the syphilis incidence in the Hengyang area during the past 4 years .Methods:Serum samples from the STD patients were detected for syphilis by RPR and TPPA. Tendency x 2 test was used for data analysis. Results:The detection rate of syphilis had year-increasing tend(x 2=15.070,P<0.01). There was no obvious difference between the detecion results by RPR and TPPA in the primary and secondary syphilis .To the latent patients,however, TPPA was superior to RPR. Moreover, RPR might diagnose non-syphilis persons as false positive. Conclusions:TPPA can be replaced by RPR to detect the primary and secondary syphilis. TPPA is superior to RPR to diagnose the latent syphilis and other non- syphilis persons. Therefore, TPPA which can quantitively detect syphilis should be applied to diagnose exactly syphilis in serology.
关键词
梅毒
检出率
血清学检测
syphilis
detection rate
serologic test
