原发性高血压患者血清生长激素、睾酮和雌二醇变化研究

Serum growth Factors,Testosterone,and Estradiol in Essential \;Hypertension

目的 :探讨原发性高血压患者血清生长激素 (GH)、睾酮 (T)和雌二醇 (E)水平的变化及其临床意义方法 :采用放射免疫法测定了 86例 EH患者和 30例非高血压患者的血清 GH,T,E水平。结果 :EH组血清 GH和 E水平显著低于对照组 (P<0 .5 5 ) ,T与对照组无明显差异 (P>0 .5 5 )。 EH组中 GH与 E水平呈显著正相关 ,但两者与 T无相关性。男性组血清 T显著高于女性组。 , , 期血清 GH和 T依次显著递减。伴心脑血管并发症组血清 GH与 T水平显著低于无并发症组 ,但 E无明显差异。结论 :EH组血清 GH和 E水平显著低于对照组。 , , 期血清 GH与 T依次显著递减。伴心脑血管并发症组血清 GH与

Aim:To investigate the changes of serum growth factor(GH),testosterone(T),and estradial(E 2) in patients of essential hypertension Methods:Serum GH,T,and estradial were studied in 86 cases of hypertension by radioimmunoassay,38 normotensive patients were served as control. Results:Serum GH and estradil were decreased significantly in hypertensives compared with that in the control group. GH and estradil were most markedly decreases in Ⅲ stage hypertensives.However,in patients complicated with cardio cerebro vascular diseases.GH and T were decreased markedly than that without complications,while no changes in estradil was found. Conclusion:GH and estradil were decreased in hypertensive patients and most markedly decreaes in Ⅲ stage hypertensives.