支架置入治疗肾血管性高血压报告

Stent Placement to Treat Renovascular Hypertension

目的 :评估支架置入治疗肾动脉狭窄的安全性和疗效。方法 :6例患者 (男 3,女 3) ,年龄 38± 17岁 ,患有严重的肾动脉狭窄 (8条病变 ) ,因单用高压球囊扩张效果不满意 ,置入球囊扩张支架。术后定期随访。结果 :1条病变残留狭窄 10 % ,其余 7条病变无残留狭窄。所有患者血压均有明显下降 ,收缩压从 16 4± 13m m Hg降至 12 7± 16 mm Hg;舒张压从 98± 11mm Hg降至 80± 10 mm Hg。 3例停用降压药物血压仍正常 ,另 3例降压药从 4种减至 2种血压仍能满意控制。平均随访 6± 2月 ,疗效能稳定维持。结论 :支架置入是治疗肾血管性高血压的安全有效方法 ,其初步疗效满意 。

Objectives:To evaluate the safety and efficacy of stent placement in patients with hypertension caused by renal artery stenoses. Methods:6 patients(3 man and 3 women), aged 14～57 years suffered from severe renal artery stenosis. Balloon expandable stents were placed in 8 arteries(diameter reduction 80%～100%), who had not been satisfactorily treated by high pressure balloon angioplasty. Mean 6 months of follow up was carried out. Results:Angiographic image were obtained after operation,there are remained stenosis 10% in one artery and all right in other 7 artery. Early clinical improvement was seen in all patients. Their mean systolic blood pressure was reduced from 164±13 mmHg to 127±16 mmHg,the diastolic blood pressure from 98±11 to 82±10 mmHg. Three of six patients no need to take antihypertensive drug maintained normal blood pressure, while another three patients reduced the antihypertensive drug. Conclusion:Renal artery stenting appears to be an effective and safe treatment for renovascular hypertension.