高同型半胱氨酸血症与高血压病关系的研究

Correlation Between Homocysteine and Primary Hypertension

目的:探讨血清同型半胱氨酸(homocysteine,Hcy)与高血压病的相关性。方法:选择85例高血压病患者和80例健康对照组,采用循环酶法测定血清同型半胱氨酸水平,同时测定叶酸、维生素B12,两组间进行比较。结果:与正常对照组比较,高血压病组血清Hcy水平升高(P<0.01),而叶酸、维生素B12下降(P<0.01);血清Hcy水平与血压(收缩压和舒张压)水平存在正相关关系(P<0.01)。结论:Hcy是高血压的危险因素之一,监测血清Hcy对于高血压的预防、诊断和治疗具有重要意义。

Objective：Tdiscuss the correlation between serum homocysteine（Hcy） and primary hypertension.Method：We selected 85 patiens with hypertension and 80 health comparison crowd,used the cyclophorase law determ ination blood serum homocysteine level and folic acid,vitaminB12,compared with two groups.Result：Hypertension group blood plasma Hcy level was higher than the healthy control group.The blood plasma Hcy level and the blood pressure（systolic pressure and diastolic pressure） has the correlational dependence.Conclsion： The serum Hcy level elation is possibly hyper independence risk factor of hypertension.