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多发性内分泌腺瘤1型及其相关的垂体腺瘤的研究 被引量：3

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摘要 多发性内分泌腺瘤1型（MEN1）是一种罕见的常染色体显性遗传病,常见的内分泌肿瘤包括甲状旁腺腺瘤、胃肠胰内分泌肿瘤和垂体腺瘤。在MEN1中,垂体腺瘤的发生率为22%~47%。目前认为：MEN1相关肿瘤发生的组织选择性与多发性内分泌腺瘤蛋白的组织选择性有关;头部MRI检查及血内分泌激素测定是垂体腺瘤筛查与诊断的重要手段;MEN1相关垂体腺瘤的治疗倾向于手术治疗。
作者 李国夫 王宁
机构地区 哈尔滨医科大学附属第一医院神经外科
出处 《中国微侵袭神经外科杂志》 CAS 2012年第5期236-238,共3页 Chinese Journal of Minimally Invasive Neurosurgery
关键词 多发性内分泌瘤病1型 垂体肿瘤 多发性内分泌腺瘤蛋白
分类号 R736 [医药卫生—肿瘤]
  • 相关文献

参考文献20

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二级参考文献18

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共引文献36

同被引文献24

  • 1孙青芳,卞留贯,赵卫国,沈建康,宁光,张天锡,罗其中.垂体泌乳素腺瘤的手术治疗[J].中华神经外科杂志,2006,22(2):109-111. 被引量：14
  • 2李小英.多发性内分泌腺瘤病[J].中国实用内科杂志：临床前沿版,2006,26(11):1763-1766. 被引量：26
  • 3Gracanin A, Dreijerink KM, van der Luijt RB, et al. Tissue selectivity in multiple endocrine neoplasia type 1-asso- ciated tumorigenesis [J]. Cancer Res, 2009, 69"(16): 6371- 6374.
  • 4I Agarwal SK, Ozawa A, Mateo CM, et al. The MEN1 gene and pituitary tumour [J]. Horm Res, 2009, 7 l(Suppl 2): 131- 138.
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  • 6Won KY, Kim GY, Lim S J, et al. Prognostic significance of fascin expression in extrahepatic bile duct carcinomas [J]. Pathol Res Pratt, 2009, 205(11): 742-748.
  • 7Hendy GN, Kaji H, Canaff L. Cellular functions of menin [J]. Adv Exp Med Biol, 2009, 668: 37-50.
  • 8Lairmore TC, Chen H. Role of menin in neuroendocrine tumorigenesis [J]. Adv Exp Med Biol, 2009, 668: 87-95.
  • 9Zhang Y, Nose V. Endocrine tumors as part of inherited tumor syndromes [J]. Adv Anat Pathol, 2011, 18(3): 206- 218.
  • 10Xu L, Li X, Feng B, Ni Y, Wang H, Wang L. A novel mutation of the MEN1 gene in a Chinese kindred with multiple endocrine neoplasia type l. Endocr J, 2010, 57 (9): 839-845.

引证文献3

二级引证文献2

中国微侵袭神经外科杂志
2012年 第5期

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