原发性干燥综合征患者焦虑情况调查及相关因素分析

Neuropsychiatric syndromes in patients with primary Sjogren′s syndrome: anxiety and relative factors

目的调查原发性干燥综合征患者焦虑状况及相关因素。方法采用Zung焦虑自评量表(SAS)评估98例原发性干燥综合征患者的焦虑状况并分析相关影响因素。结果 98例患者SAS评分为(35.77±7.44)分,10例患者(10.2%)SAS评分≥50分。躯体疲劳是该病患者焦虑情绪的主要表现。以性别、年龄、病程等因素分组,同因素组间对比差异无统计学意义。结论原发性干燥综合征患者存在明显焦虑情绪,其产生原因有待于进一步研究,可能由于患者神经系统受损引起。

Objective To assess the presence and degree of anxiety in a group of patients with primary Sjogren′s syndrome（PSS） and to identify factors contributing to the mental changes.Methods We identified 98 subjects who met the American-European consensus criteria for the classification of PSS.Anxiety was assess with Self-rating Anxiety Scale（SAS）.Associations with anxiety were compared using test.Results Abnormal anxiety defined as SAS score of ≥50 was present in 10 patients（10.2%）.The average SAS score of these patients＇ was（35.77±7.44）which was extremely higher than norm in China.Gender,age,marriage status and disease duration were not the factors contributing to anxiety.Conclusion The results indicate that patients with primary Sjogren′s syndrome appear to be an increased risk of anxiety.It could be a result of neural system involvement.