如何通过黏膜活检和超声内镜提供IBD的诊断线索

Mucosal biopsy and endoscopic ultrasonography in the diagnosis of inflammatory bowel disease

炎症性肠病(IBD)包括克罗恩病和溃疡性结肠炎,与肠道结核、淋巴瘤等均以肠道溃疡为特征,诊断往往依赖病理诊断金标准。但在临床上由于病理活检取材的局限,常不能提供疾病确诊的病理学依据,因而相互间的鉴别诊断较困难,常为临床上的治疗带来困惑。本文根据作者长期的内镜活检和超声内镜检查经验,介绍如何通过黏膜活检和超声内镜提供IBD的诊断线索,为临床医生确诊该类疾病提供借鉴和帮助。

Inflammatory bowel disease （IBD） includes Crohn＇ s disease and ulcerative colitis, which is characterized by intestinal ulcers. The same as intestinal tuberculosis, lymphoma and other disorders were diagnosed by histopatholo- gy. Gaining pathological evidence for diagnosis is difficult because of limitation of biopsy depth, differential diagnosis is hard, often puzzles physicians about clinical treatment. On the basis of extensive experience in endoscopic biopsy and endoscopic ultrasonography, we introduced methods to search diagnostic clue through mucosal biopsy and endoscopic ul- trasonography and to help clinicians identify such diseases.