HRT-Ⅱ监测POAG复合小梁切除术后视盘主要参数变化

Alteration of major parameters of optic disk after compound trabeculectomy in primary open angle glaucoma patients with HRT-Ⅱ

目的:通过海德堡共焦激光眼底扫描仪(HRT-Ⅱ)随访监测不同病程的原发性开角型青光眼(POAG)患者术后视盘结构参数的变化,评价HRT-Ⅱ在抗青光眼术后随访的可行性。方法:对20例20眼POAG行复合小梁切除术,其中早期8眼、进展期及晚期12眼,术后眼压控制稳定不需联合药物治疗,术后随访2a,分别于术后3,6,12,24mo行HRT-Ⅱ扫描。结果:早期、进展期及晚期20眼视盘结构主要参数视杯/视盘面积比(C/D)、盘沿面积(RA)、平均视网膜神经纤维层厚度(mRNFL)手术前后比较差异有统计学意义(P<0.05),视盘上下象限mRNFL厚度手术前后比较差异有统计学意义(P<0.05)。结论:HRT-Ⅱ应用于POAG患者术后随访监测是一种客观的观察方法,具有高度可重复性、客观性。

AIM：To evaluate the feasibility of application with HRT-Ⅱ to detect morphological alteration of optic disc in primary open angle glaucomatous patients after complex trabeculetomy. METHODS： Totally 20 eyes of 20 cases with different stages of primary open angle glaucoma （POAG）were performed with complex trabeculectomy. All patients＇ IOP were controlled without medicines. The follow-up period was 24 months. HRT-Ⅱscanning was differently undergone in postoperation 3,6,12 and 24 months. RESULTS： There was significant difference （P0.05） between preoperation and postoperation in cup/disk area ratio （C/D）, rim area （RA）, mean and superior /inferior retinal nerve fibre layer （mRNFL） in all patients with different stages. CONCLUSION：HRT-Ⅱ can be applied to detect the post-operative morphological alteration of optic disc in POAG patients with high objectivity and repeatability.