期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

矿物质与骨代谢紊乱增加慢性肾脏病患者病死率 被引量：8

原文传递
导出
摘要 慢性肾脏病一矿物质与骨代谢紊乱（CKD—MBD）包括在CKD患者中出现的矿物质代谢紊乱、肾性骨营养不良和血管钙化。在CKD患者，矿物质代谢紊乱表现为血钙磷失衡、维生素D缺乏、继发性甲状旁腺功能亢进、成纤维细胞生长因子23（FGF23）增加；肾性骨营养不良表现为骨质疏松和（或）高转化性、低转化性、混合性骨病；
作者 贾俊亚 林珊
机构地区 天津医科大学总医院肾内科
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 2012年第5期413-416,共4页 Chinese Journal of Nephrology
基金 国家自然科学基金（30800529） 天津市科委天津市应用基础及前沿计划（10JCYBJC11700）
关键词 骨代谢紊乱 慢性肾脏病 矿物质 患者 继发性甲状旁腺功能亢进 肾性骨营养不良 病死率 成纤维细胞生长因子
分类号 R692.5 [医药卫生—泌尿科学]
  • 相关文献

参考文献31

  • 1Kidney Disease: Improving Global Outcomes (KDIGO) CKDMBD Work Group. KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder (CKDMBD). Kidney Int, 2009, 76: S1-S130.
  • 2Slatopolsky E, Moe S. 50 years of research and discovery in chronic kidney disease and mineral & bone disorder: the central role of phosphate. Kidney Int Suppl, 2011, 121: S1- S2.
  • 3Tentori F, Blayney MJ, Albert JM, et al. Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis, 2008, 52: 519- 530.
  • 4Noordzij M, Korevaar JC, Boeschoten EW, et al. The Kidney Disease Outcomes Quality Initiative (K/DOQI) Guideline for Bone Metabolism and Disease in CKD: association with mortality in dialysis patients. Am J Kidney Dis, 2005, 46: 925-932.
  • 5Noori N, Kalantar-Zadeh K, Kovesdy CP, et al. Association of dietary phosphorus intake and phosphorus to protein ratio with mortality in hemodialysis patients. Clin J Am Soc Nephrol, 2010, 5: 683-692.
  • 6Block GA, Matin KJ, de Francisco ALM, et al. Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis. New Engl J Med, 2004, 350: 1516-1525.
  • 7Block GA, Klassen PS, Lazarus JM, et al. Mineral metabolism, mortality, and morbidity in maintenance hemodialysis. J Am Soc Nephrol, 2004, 15: 2208-2218.
  • 8Kalantar-Zadeh K, Kuwae N, Regidor DL, et al. Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients. Kidney Int, 2006, 70: 771-780.
  • 9Guideline Working Group, Japanese Society for Dialysis Therapy. Clinical practice guideline for the management of secondary hyperparathyroidism in chronic dialysis patients. Ther Apher Dial, 2008, 12: 514-525.
  • 10Nakai S, Akiba T, Kazama J, et al. Effects of serum calcium, phosphorous, and intact parathyroid hormone levels on survival in chronic hemodialysis patients in Japan. Ther Apher Dial, 2008, 12: 49-54.

二级参考文献13

  • 1华琦,谭静,刘东霞,闻静,邢绣荣.高血压病患者颈-股动脉和颈-桡动脉脉搏波速度改变及其影响因素[J].中华心血管病杂志,2005,33(12):1088-1091. 被引量：41
  • 2Foley RN,Parfrey PS,Sarnak MJ.Clinical epidemiology of cardiovascular disease in chronic renal disease.Am J Kidney Dis,1998,32:S112-S119.
  • 3Mizobuchi M,Towler D,Slatopolsky E.Vascular calcification:the killer of patients with chronic kidney disease.J Am Soc Nephrol,2009,20:1453-1464.
  • 4London GM,Guerin AP,Marchais S,et al.Arterial media calcification in end-stage renal disease:Impact on all-cause and cardiovascular mortality.Nephrol Dial Transplant,2003,18:1731 -1740.
  • 5Blather J,Guerin AP,Pannier B,et al.Impact of aortic stiffness on survival in end-stage renal disease.Circulation,1999,99:2434-2439.
  • 6Upadhyay A,Hwang SJ,Mitchell GF,et al.Arterial stiffness in mild-to-moderate CKD.J Am Soc Nephrol,2009,20:2044-2053.
  • 7Kimoto E,Shoji T,Shinohara K,et al.Regional arterial stiffness in patients with type 2 diabetes and chronic kidney disease.J Am Soc Nephrol,2006,17:2245-2252.
  • 8Lemos MM,Jancikic AD,Sanches FM,et al.Pulse wave velocity -a useful tool for cardio vascular surveillance in pre-dialysis patients.Nephrol Dial Transplant,2007,22:3527-3532.
  • 9Proudfoot D,Shanahan CM.Biology of calcification in vascular cells:intima versus media.Herz,2001,26:245-251.
  • 10Shao SJ,Cai J,Towler DA.Molecular mechanisms of vascular calcification:lessons learned from the aorta.Arterioscler Thromb Vasc Biol,2006,26:1423-1430.

共引文献8

同被引文献76

引证文献8

二级引证文献59

中华肾脏病杂志
2012年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部