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脱色性色素失禁症1例

A Case of Incontinentia Pigmenti Achromicans
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摘要 患儿男,5岁。面部、躯干、四肢出现色素减退斑5年。皮肤科情况:面部、躯干、四肢可见特殊形状的色素减退斑,大多数白斑呈线状或旋涡状,边界清楚。激光共聚焦扫描显微镜检查(手臂):与周围皮肤对照,浅色斑区基底层色素减少,基底细胞环大致存在,部分基底环可见点状缺失,真皮乳头及浅层可见少许嗜黑素细胞及稀疏炎细胞浸润。诊断:脱色性色素失禁症。 A 5-year-old boy presented with macular hypopigmentation of special patterns over the face,trunk and limbs 5 years before.Physical examination showed bizarre and patterned whitish patches spread over the face,trunk and limbs,and the most of whitish patches manifested as line or vortex with distinct boundary.Laser confocal scanning microscope showed that compare with the normal skin,pigment in the stratum basale of the whitish patches was decreased,the rings of the cells in the stratum basale were roughly existed with pointlike lack in some part,very few melanocytes and inflammatory infiltrates were seen in the dermal papilla and the shallow layer.Diagnosis of incontinentia pigmenti achromicans was made.
出处 《中国皮肤性病学杂志》 CAS 北大核心 2012年第6期530-531,共2页 The Chinese Journal of Dermatovenereology
关键词 色素失禁症 无色素性 Incontinentia, pigmenti aehromians
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参考文献6

  • 1lto M. Studies of Melanin XI. Incontinentia pigmenti a .hr mians: A singulm" ease of naevus depigmentosus systematies b ilateralis [ J ]. Tohoku J ExpMed , 1952, 55 (Suppl) :57 -59.
  • 2Schwartz MF Jr, Esterly NB, Fretzin DF,et al. Hy- pomelanosis of lto ( incontinentia pigmenti achromi- cans) : a neurocutaneous syndrome [ J ]. J Pediatr, 1977,90 ( 2 ) :236 - 240.
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  • 5杜娟,张建中.无色素性色素失禁症并发白癜风[J].临床皮肤科杂志,2008,37(2):99-100. 被引量:1
  • 6杨凡,周利平,陈柳青,黄萌,王玮蓁,段逸群.脱色性色素失禁症2例[J].中国皮肤性病学杂志,2011,25(10):796-796. 被引量:1

二级参考文献6

  • 1Schwartz MF, Eslerly NB, Fretzin DF, et al. Hypomelanosis of lto ( incontinentia pigmenti achromians) : a neurocutaneous syndrome[ J]. J Pediatr, 1977, 90( 2 ) : 236 - 240.
  • 2Ruiz-Maldonado R, Trussaint S, Tamayo L, el al. Hypomelanosis of ho:diagnostic criteria and repot1 of 41 cases [ J ]. Pediatr Dermatol, 1992,9 ( 1 ) : 1- 10.
  • 3韩传恩 谢继红.脱色性色素失禁症1例.中国皮肤性病学杂志,7(4):263-263.
  • 4Schwartz MF Jr, Esterly NB. Fretzin DF, et al. Hypomelanosis of Ito (incontinentia pigmenti achromians): a neurocutaneous syndrome[J]. J Pediatr, 1977, 90(2): 236-240.
  • 5Failla P, Romano C,Schepis C. Hypomelanosis of Ito: a syndrome requiring a multisystem approach[J]. J Dermatol, 1997, 38 (2): 65-70.
  • 6Ruiz-Maldonado R, Toussaint S, Tamayo L, et al. Hypomelanosis of Ito: diagnostic criteria and report of 41 cases[J]. Pediatr Dermatol, 1992, 9(1): 1-10.

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