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炎症与干细胞:niche——不只是温床 被引量：1

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摘要 干细胞（stem cell）是一种未充分分化、尚不成熟的细胞，具有自我更新和多向分化的潜能。由于干细胞具有再生各种组织器官甚至人体的潜在功能，医学界称之为“万用细胞”。根据干细胞所处的发育阶段分为胚胎干细胞（embryonic stem cell）和成体干细胞（somatic sten cell）。干细胞的发育受多种内在机制和微环境因素的影 响。
作者 孔祥伟 丁寅 金岩
机构地区 第四军医大学口腔医学院正畸科 第四军医大学口腔医学院组织工程中心
出处 《医学争鸣》 CAS 北大核心 2012年第2期21-23,共3页 Negative
关键词 胚胎干细胞 温床 炎症 多向分化 发育阶段 成体干细胞 自我更新 潜在功能
分类号 R329.2 [医药卫生—人体解剖和组织胚胎学]
  • 相关文献

参考文献10

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二级参考文献47

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共引文献29

同被引文献69

  • 1闫国和,粟永萍,艾国平,屈纪富,冉新泽,程天民,庞学利,肖红.羊膜负载骨髓间充质干细胞与表皮细胞对放创性皮肤损伤促愈合研究[J].中国修复重建外科杂志,2004,18(6):497-501. 被引量：22
  • 2耿献辉,余春艳,邓志宏,张勇杰,陆伟,温宁,薛洁,张锐红,康晓军,金岩.骨髓间充质干细胞复合组织工程化脱细胞真皮基质构建组织工程皮肤[J].中国美容医学,2007,16(4):443-446. 被引量：8
  • 3张媛,郭维,胡吟燕,郑贵亮,翟所强.大鼠耳蜗毛细胞前体细胞与耳蜗间质细胞共培养的实验研究[J].听力学及言语疾病杂志,2007,15(3):205-207. 被引量：6
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  • 6Cunha G R. Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate. Cancer, 1994, 74(3 Suppl): 1030-1044.
  • 7Rubio D, Garcia S, De la Cueva, et al. Human mesenchymal stem cell transformation is associated with a mesenchymal-epithelial transition. Experimental Cell Research, 2008, 314(4): 691-698.
  • 8Keiko Inada, Shinji Hayashi, Taisen Iguchi, et al. Establishment of a primary culture model of mouse uterine and vaginal stroma for studying in vitro estrogen effects. Experimental Biology and Medicine, 2006, 231(3): 303-310.
  • 9Jiarong Liu, Jeremy J Mao, Lili Chen. Epithelial-mesenchymal interactions as a working concept for oral mucosa regeneration. Tissue Engineering Part B: Reviews, 2011, 17(1): 25-31.
  • 10Liu J, Huang J, Lin T, et al. Cell-to-cell contact induces human adipose tissue-derived stromal cells to differentiate into urothelium-like cells in vitro. Biochemical and Biophysical Research Communications, 2009, 390(3): 931-936.

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医学争鸣
2012年 第2期

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