血管生成素／Tie2受体通路与白血病的关系
摘要
血管生成素（Angs）家族是新近发现的促血管新生因子家族，有4个成员Ang1，Ang2，Ang3和Ang4。研究发现血管生成素在白血病肿瘤血管新生中发挥重要作用，已成为白血病独立的预后因子。
出处
《国际输血及血液学杂志》
CAS
2012年第3期245-247,共3页
International Journal of Blood Transfusion and Hematology
基金
河北省自然科学基金项目（c2008000660）
参考文献26
-
1Folkman J. The role of angiogenesis in tumor growth. Semin Cancer Biol, 1992,3(2) : 65-71.
-
2Shih TT, Hou HA, Liu CY, et al. Bone marrow angiogenesis magnetic resonance imaging in patients with acute myeloid leukemia: peak enhancement ratio is an independent predictor for overall survival. Blood, 2009, 113(14):3161-3167.
-
3Kim KT, Choi HH, Stinmetz MO, et al. Oligomerization and mu[timerization are critical ~or angiopoietin-1 to bind and phosphorylate Tie2. J Biol Chem, 2005, 280(20):20126-20131.
-
4Shim WS, Ho IA, Wong PE. Angiopoietin..a TIE(d) balance in tumor angiogenesis. Molecular Cancer Research, 2007, 5: 655- 665.
-
5Kim KL, Shin IS, Kim JM, et al. Interaction between Tie receptors modulates angiogenic activity o{ angiopoietin 2 in endothelial progenitor cells. Cardiovasc Res, 2006, 72 (3) : 394- 402.
-
6Loges S, Heil G, Bruweleit M, et al. Analysis of concerted expression of angiogenic growth factors in acute myeloid leukemia: expression of angiopoietin-2 represents an independent prognostic {actor for overall survival. J Clin Oncol, 2005,23 (6) : 1109-1117.
-
7Arai F, Hirao A, Ohmura M, et al. Tie2/angiopoietin-1 signaling regulates hematopoietie stem cell quiescence in the bone marrow niche. Cell, 2004,118(2) :149-161.
-
8Madlambayan GJ, Meacham AM, Hosaka K, et al. Leukemia regression by vascular disruption and antiangiogenic therapy. Blood,2010, 116(9) : 1539-1547.
-
9Reikvam H, Hatfield KJ, Lassalle P, et al. Targeting the angiopoietin (Ang)/Tie-2 pathway in the crosstalk between acute myeloid leukaemia and endothelial cells., studies of Tie-2 blocking antibodies, exogenous Ang-2 and inhibition of constitutive agonistic Ang-1 release. Expert Opin lnvestig Drugs, 2010, 19 (2) :169-183.
-
10Hou HA, Chou WC, Lin LI, et al. Expression of angiopoietins and vascular endothelial growth factors and their clinical significance in acute myeloid leukemia. Leuk Res, 2008,32 (6) 904-912.
-
1尚卫华,王康.内皮抑素在直肠癌中的表达与血管生成的关系[J].现代肿瘤医学,2007,15(8):1139-1140. 被引量：1
-
2许辉,罗洁.乳腺癌中的Wnt信号通路和雌激素-受体通路[J].长沙医学院学报,2006(1):43-45.
-
3陈俞霖,罗洁.人乳腺癌Wnt通路异常表达和雌激素受体阳性表达的关系[J].新闻天地（下半月刊）,2010(12):72-73.
-
4曾晓梅,侯梅.雌、孕激素受体在非小细胞肺癌中的研究进展[J].肿瘤预防与治疗,2014,27(4):194-198. 被引量：4
-
5冀洪海,杨勇,胥欣,王斯华,孙岩,高玉光.Tie2受体在口腔鳞癌中的表达[J].口腔颌面外科杂志,2008,18(6):386-389. 被引量：3
-
6程健,尚卫华.Tie2受体在直肠癌组织中的表达与调控作用[J].现代肿瘤医学,2008,16(3):398-399.
-
7王康,尚卫华,贾蓬勃,李徐奇,魏光兵.血管生成素受体Tie2在直肠癌中的表达及作用[J].西安交通大学学报（医学版）,2006,27(6):599-601. 被引量：4
-
8陈立波,郑启昌,王国斌,杨镇.Tie2受体在人肝癌的表达及其与血管生成和肿瘤发展的关系[J].中华肝胆外科杂志,2002,8(8):487-490. 被引量：1
-
9廖振林,侯利华,陈薇,童贻刚.Tie2受体研究进展及其在抗肿瘤治疗中的应用[J].生物技术通讯,2004,15(4):383-385. 被引量：1
-
10王辉,刘茵,王正晖,韦淑萍.血管生成素及其受体Tie2在婴幼儿血管瘤表达的研究[J].中国急救复苏与灾害医学杂志,2014(6):516-519.
