原发性甲状旁腺功能亢进症合并甲状腺疾病15例临床分析

Clinical analysis on 15 cases with primary hyperparathyroidism complicating thyroid diseases

目的探讨原发性甲状旁腺功能亢进症(PHPT)患者合并甲状腺疾病的临床特征。方法回顾性分析29例手术治疗并经病理检查确诊的PHPT患者的临床资料。结果29例PHPT患者中,无甲状腺疾病组14例,合并甲状腺疾病组15例(51.7%)。其中,甲状腺良性病变10例(结节性甲状腺肿9例,桥本氏甲状腺炎1例),恶性病变5例(甲状腺乳头状癌4例,甲状腺隐匿性癌1例)。合并甲状腺疾病组的平均年龄大于无甲状腺疾病组(P<0.05)。结论 PHPT患者合并甲状腺疾病的发病率高,且甲状腺恶性病变较多。

Objective To summarize the clinical features of primary hyperparathyroidism（PHPT） complicated with thyroid diseases. Methods Data of 29 PHPT patients underwent parathyroidectomy were analyzed retrospectively. Results Of 29 PHPT patients,15（51.7%） cases complicated with thyroid diseases,which included 10 benign lesions（nodular goiter in 9 cases and Hashimoto＇s thyrioditis in 1 case） and 5 malignant cases（papillary thyroid carcinoma in 4 cases and occult thyroid cancer in 1 case）.The mean age of PHPT cases with thyroid diseases was significantly higher than that without thyroid diseases（P0.05）. Conclusion PHPT patients have a high incidence of complicating with thyroid diseases,of which malignant lesions occur frequently.