摘要
CD151是近些年来发现的一个新的促癌基因,属于跨膜四蛋白超家族成员,它是第一个在人类中被证实的促癌基因。跨膜四蛋白被认为具有一系列广泛的细胞功能,包括在细胞增殖、融合,肿瘤的生长、迁移中都起十分重要的作用,本文就CD151与消化系统肿瘤的关系进行综述。
CD151 is known as the only new promote cancer ongogene in recently,belong to a family of proteins characterized by four highly conserved transmembrane domains,and was thought to be the first new promote cancer ongogene in the family.These proteins are thought to be involved in the regulation of a broad range of cellular functions,including fertilization,platelet aggregation,mobility,differentiation and tumor metastasis,adhension,migration and angiogenesis.This article reviews CD151 in relationship with digestive tract system tumor.
出处
《现代肿瘤医学》
CAS
2012年第6期1294-1297,共4页
Journal of Modern Oncology
基金
全军医学科技创新基金(编号:08MA053)