复方阿替卡因在口腔局部浸润麻醉拔牙中对高血压患者血压和脉搏的影响

Influence of compound articaine on blood pressure and pulse in tooth extraction under oral cavity local infiltration anesthesia in patients with hypertension

目的探讨含有肾上腺素复方阿替卡因局部麻醉药在拔牙过程中对高血压患者血压和脉搏的影响及其安全性。方法选择局部麻醉前血压控制在160/90mm Hg(1mm Hg=0.133kPa)以下、脉搏小于或等于100次/分钟的60例高血压患者分为两组,每组30例,实验组用含肾上腺素复方阿替卡因,对照组用不含肾上腺素的2%利多卡因麻醉,分别测量并记录浸润麻醉前、麻醉后的血压和脉搏,进行对比分析,并对局部麻醉效果进行评价。结果实验组和对照组麻醉前后血压、脉搏无明显差异,差异无统计学意义(P>0.05),患者局部麻醉效果无明显不适。结论麻醉前血压控制在160/90mm Hg以下、脉搏小于或等于100次/min的高血压患者,在临床拔牙中使用复方阿替卡因局部麻醉对血压及脉搏无显著影响,麻醉操作是安全有效的,并且显著增强局部麻醉效果。

Objective To discuss the influence and safety of local anesthetic compound articaine containing epinephrine on blood pressure and pulse in the tooth extraction process in the patients with hypertension. Methods 60 cases of hypertension, blood pressure≤160/90 mm Hg and pulse 4100 beats/min before local anesthesia, were selected and divided into two groups,30 cases in each group. The experimental group used compound articaine containing epinephrine and the control group used 2% lidocaine without epinephrine. Blood pressure and pulse rate were measured and recorded before and after infiltration anesthesia for performing the comparative analysis and evaluating the effects of local anesthesia. Results In the experimental group and the control group,blood pressure and pulse had no obvious difference before and after anesthesia without statistical significance （P〉0.05）. No obvious discomfort existed in the patients with local anesthesia. Conclusion In the hypertensive patients with blood pressure ;160/90 mm Hg and pulse≤100 heats/rain before anesthesia,compound articaine for local anesthesia has no obvious influence on blood pressure and pulse in clinical dental extraction,anesthetic operating is safe and effective,and significantly en- hances the local anesthetic effect.