摘要
慢性疼痛中,神经元-脊髓小胶质细胞间的信号分子可以激活脊髓小胶质细胞,而激活的脊髓小胶质细胞可以释放多种与慢性疼痛有关的活性物质。实验研究表明,脊髓小胶质细胞表面受体的上调及细胞内激酶的激活在细胞的激活和慢性疼痛的发生和发展中起重要作用。
Many substances can activate microglia in the spinal cord,and activated microglia in the spinal cord can release a variety of active and pain-related substances.Experimental studies have shown that spinal cord microglia cell surface receptors and intracellular kinase activations play important roles in cell activation and chronic pain.
出处
《复旦学报(医学版)》
CAS
CSCD
北大核心
2012年第3期324-326,330,共4页
Fudan University Journal of Medical Sciences