不同方法在评价男性阻塞性睡眠呼吸暂停综合征患者勃起功能障碍中的应用

Different Evaluation Methods About Erectile Dysfunction on the Male Patients with Obstructive Sleep Apnea Syndrome Patients

目的分别采用夜间阴茎勃起(nocturnal penile tumescence,NPT)监测与国际勃起功能指数评分5项(5-item version of the international index of erectile function,IIEF-5)评估男性阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome,OSAS)患者勃起功能障碍(erectile dysfunction,ED)的发病率,并讨论OSAS患者发生性功能障碍的可能机制。方法诊断为OS-AS患者84名,分成NPT组(40名)和IIEF-5组(44名)。选取42名健康成年男性作为对照组,需同时完成NPT监测和IIEF-5自评。所有研究对象均测定性激素水平,包括PRL、TT、E2、FSH、LH。结果与对照组比较,NPT组患勃起功能障碍的概率为40.00%,而IIEF-5组有勃起功能障碍的概率为31.82%,两者差异无统计学意义(P>0.05),且3组之间的性激素水平差异亦无统计学意义(P>0.05)。结论在男性OSAS患者中有较高的勃起功能障碍发病率,且其性功能障碍的发生与性激素水平无关。

Objective The nocturnal penile tumescence（NPT） and the 5 - item version of the International Index of Erectile Function （ IIEF - 5） are respectively used to evaluate the incidence of ED on OSAS patients, and research the possible mechanism of the sexual dysfunction about them. Methods There are 84 patients diagnosed with OSAS by polysomnography（PSG） , 40 of them are in NPT group and 40 are in fIEF - 5 group. Other 42 healthy adult males are as control group who should finish monitoring NPT and evaluating of IIEF -5. All the groups are tested sex hormone levels including PRL, TT, E~, FSH, LH. Results Compared with the control group, the incidence of ED in NPT group is 40% , while 31.82% in IIEF -5 group, which has no significant change（P 〉0.05）, and the sex hormones levels of three groups have no significant change（P 〉 O. 05）. Conclusion The male patients with OSAS have a higher incidence of erectile dysfunction, and sex hormone levels have nothing to do with the sexual dysfunction.