舒利迭联合孟鲁司特钠治疗支气管哮喘的临床研究

Clinical study on montelukast sodium combined with seretide in bronchial asthma treatment

目的观察舒利迭联合孟鲁斯特钠应用对支气管哮喘的症状体征改善情况，分析其临床治疗效果。方法选取经我科治疗的轻、中度支气管哮喘患者120例，随机分为两组，每组60例。对照组使用布地奈德治疗，观察组联合用药。比较两组患者的临床治疗效果。结果①进过6周的治疗后进行组内比较：对照组与观察组患者的MMEF、FEVl、PEF均较治疗前有所改善（P〈0．05）。两组患者治疗后进行组间比较，观察组肺功能指标改善明显优于对照组（P〈0．05）。②观察组显效率明显高于对照组沪〈0．05）。结论舒利迭联合孟鲁斯特钠治疗支气管哮喘临床效果明显．值得推广使用。

Objective To observe and analyze the clinical effect of montelukast sodium combined with seretide in treatment for bronchial asthma. Methods 120 patients with bronchial asthma were divided into observation group and control group, 60 patients for each group. The control group received the budesonide, and observation group received the treatment of montelukast sodium combined with seretide. After 6 weeks of treatment, the clinical effect of two groups were compared. Results ① The observation indicators such as MMEF,FEV1 and PEF had both improved in both groups compared to those before treatment （P〈0.05）, and observation group had improved better than control group after treatment （P〈0.05）. ② Observation group had better clinical effect than control group （P〈0.05）.Conclusion Montelukast sodium combined with seretide has significant clinical effect in bronchial asthma.