壳聚糖宫颈抗菌膜联合CO2激光治疗宫颈糜烂疗效观察

Combination of Chitosan-cervical-antibiotics-membrane and CO2 laser for cervical erosion

目的探讨宫壳聚糖宫颈抗菌膜联合CO2激光治疗宫颈糜烂的临床疗效。方法将426例宫颈糜烂作为研究对象，随机分成治疗组213例和对照组213例。治疗组在CO2激光治疗后立即放置壳聚糖宫颈抗菌膜；对照组单用CO2激光治疗。结果治疗组一次性痊愈204例（96％），二次性痊愈9例（4％）；对照组一次性痊愈176例（82％），二次性痊愈37例（18％）。结论壳聚糖宫颈抗菌膜能明显促进宫颈CO2激光治疗术后创面愈合，减少阴道流液、流血时间及量。

Objective To explore the clinical efficacy of the combination of Chitosan-cervical-antibiotics- membrane and CO2 for cervical erosion. Methods 426 patients with cervical erosion were randomly divided into treatment group and control group, 213 cases for each. The treatment group were treat with Chitosan-cervical-antibiotics-membrane after CO2 laser surgery, and the control group were treat with CO2 laser surgery only. Results 204 （ 96% ） in the treatment group were cured after one treatment, and 9 needed secondary treatment. 176（ 82% ） in the control group were cured after one treatment, and 37 needed secondary treatment. Conclusions After CO2 laser surgery of cervical erosion, Chitosan-cervical-antibiotics-membrane can improve the wound＇s coalescence, shorten the time and decrease the volume of vaginal bleeding and fluid flow.