沙利度胺治疗慢性病贫血临床研究

Clinical Research of Thalidomide for the Treatment of Anemia of Chronic Disease

目的:评估沙利度胺治疗慢性病贫血的临床疗效,观察其不良反应。方法:对2011年3月至2011年10月我院26例慢性病贫血患者的临床资料进行分析,采用沙利度胺治疗,必要时输注红细胞纠正贫血。结果:26例患者中有效15例,有效率57.7%,无效11例,无效率42.3%,其中死亡2例。结论:沙利度胺治疗慢性病贫血有较好疗效,不良反应小,值得进一步推广。

Objective ：To estimate the clinical effect of thalidomide in treating anemia of chronic disease （ACD） and observe its adverse reactions. Methods：26 patients diagnosed as ACD from March, 2011 to October, 2011 were treated with thalidomide and injected with red blood cell （RBC） for treating anemia necessarily. Results： 15 patients had achieved good remission, the remission rate was 57.7%, while 11 patients had achieved no effect, the un-effective rate was 42.3%, 2 patients died. Conclusion：Thalidomide is an effective and safe drug in treating ACD with side effects being mild, so it is worth further spreading.