米索前列醇联合缩宫素预防产后出血的疗效观察

The curative effects of Misoprostol combined with Oxytocin in treating postpartum hemorrhage

目的:观察米索前列醇联合缩宫素预防产后出血的疗效。方法:选择2009年1月至2010年12月我院住院经阴道分娩的产妇126例,随机分为两组:观察组71例,于胎儿娩出后立即予缩宫素20 U肌注,同时口服米索前列醇600μg。对照组55例,于胎儿娩出后立即予缩宫素20 U肌注。观察两组产妇胎儿娩出后至产后2 h的阴道出血量。结果:两组产妇的年龄、孕周、体重及新生儿体重方面差异无统计学意义(P>0.05)。两组产妇胎儿娩出后至产后2h的阴道出血量相比,差异有显著性意义(P<0.05)。结论:米索前列醇联合缩宫素预防产后出血,疗效优于单用缩宫素,值得临床推广应用。

Objectlve：To observe The curative effects of Misoprostol combined with Oxytocin in treating postpartum hemorrhage. Methods：Selection of 126 mothers by the vaginal delivery form January, 2009 to December, 2010 in our hospital were randomly divided into two groups： the observation group 71 examples, the babies immediately after childbirth goes out to oxytocin 20 U muscle note, and oral misoprostol 600 t^g. The control group 55 cases, of the fetal childbirth goes out to oxytocin immediately after 20 U muscle note. Observe the two groups of maternal postpartum fetal childbirth after 2 hours to the vaginal blood loss. Results： The maternal age, gestational age, weight, and the weight of the new-born, had no statistically significant differences （ P 〉 0. 05）. The vaginal of blood loss, during the 2 hours after childbirth, had significant difference （ P 〈 0.05 ）. Conclusion： Misoprostol combined with Oxytocin in preventing and treating postpartum hemorrhage is more effective then using oxytocin only. It is worthy of clinical application.