分子马达的输运方式研究进展

Research Progress on Transport Ways of the Molecular Motors

分子马达(molecular motor)是生物体细胞内一类具有马达功能的蛋白质大分子,几乎执行了生物体的所有生命活动,其中物质的输运是分子马达的一项重要功能。以往人们一直认为分子马达都是沿着单一轨道单独来输运物质,但随着实验的发展,研究发现分子马达的输运方式多种多样,并且输运过程与多种疾病有关。就分子马达的输运方式最新进展进行综述,阐述分子马达在体内可能的输运方式及与输运过程相关的疾病,最后总结并展望未来。

Molecular motors are protein that perform all tasks vital to the life. Intracellular transport is a very important task. In the past years, people insisted that individual molecular motor transported ＇cargo＇ along single track. But in recent years, various transport ways of molecular motors have been observed from experiments. In addition, research results show that many diseases associate with transport of molecular motors. The new process about transport ways of molecular motors is summarized, including the possible transport behavior patterns of molecular motors and the related diseases. A summary is given and possible future directions are discussed.