摘要
Controlling microbubble dynamics to produce desirable biomedical outcomes when and where necessary and avoid deleterious effects requires advanced knowledge, which can be achieved only through a combination of experimental and numerical/ analytical techniques. The present communication presents a multi-physics approach to study the dynamics combining viscous- inviscid effects, liquid and structure dynamics, and multi bubble interaction. While complex numerical tools are developed and used, the study aims at identifying the key parameters influencing the dynamics, which need to be included in simpler models.
Controlling microbubble dynamics to produce desirable biomedical outcomes when and where necessary and avoid deleterious effects requires advanced knowledge, which can be achieved only through a combination of experimental and numerical/ analytical techniques. The present communication presents a multi-physics approach to study the dynamics combining viscous- inviscid effects, liquid and structure dynamics, and multi bubble interaction. While complex numerical tools are developed and used, the study aims at identifying the key parameters influencing the dynamics, which need to be included in simpler models.
基金
supported by the National Institute of Biomedical Imaging and Bioengineering at NIH,under SBIR Phase Ⅰ and Phase Ⅱ programs
