摘要
就国内外主要毒蛇的蛇毒组分、对凝血系统的影响及蛇毒在医药领域的应用进行了综述.蛇毒的化学成分十分复杂,主要包括酶、神经毒性多肽、神经生长因子、膜活性多肽及其他生物活性肽,其中酶类包含多种与凝血系统、纤溶系统相关的成分.蛇毒在医药领域具有非常重要的作用,主要有促凝作用、溶栓作用、镇痛作用、降压作用和抗肿瘤作用.
It was overviewed the composition of snake venom, the effects of snake venom fractions on blood coagulation system, and the medical applications. The chemical composition of snake venom is very complex, containing the enzymes, neurotoxie polypeptide, nerve growth factor, active membranous peptides and other biologically active peptides. The enzymes contain a variety of components which are closely related with coagu- lation system and fibrinolytic system. The component of venom has a very important role in the medical fields, such as procoagulant effect, thrombolytic effect, analgesic effect, antihypertensive effect and antineoplastic effect.
出处
《浙江师范大学学报（自然科学版）》
CAS
2012年第2期189-194,共6页
Journal of Zhejiang Normal University:Natural Sciences
基金
浙江师范大学博士科研启动基金资助项目(ZC304010086)
关键词
蛇毒
活性肽
凝血系统
镇痛作用
抗肿瘤作用
snake venom
active peptides
blood coagulation system
analgesic effect
antineoplastic effect
