多波长线性回归紫外分光光度法同时测定复方阿斯匹林片中的三组分

Simultaneous Determination of Three Components in Aspirin Compound Tablets by Improved Multiwavlength Linear Regression Ultraviolet Spectrophotometry

用改进的多波长线性回归分光光度法同时测定了复方阿斯匹林片中三组分的含量 ,模拟样品中阿斯匹林、非那西丁、咖啡因的平均回收率分别为 1 0 0 .31 %、99.87%、1 0 0 .77% ,相对标准偏差分别为 0 .35%、0 .2 5%、1 .37% ( n=1 0 )。对四个批号实际样品的测定结果与标准方法一致 ,适于复方阿斯匹林片的常规分析。

Aspirin,phenacetin and caffeine in aspirin compound tablets were determined simultaneously by using improved multiwavelength linear regression spectrophotometry.The average recovery of these components in synthetic samples were 100.31%,99.87% and 100.77% and relative standard deviations of 0.35%, 0.25% and 1.37% respectively (n=10).The results of determination for four batches of actual samples agreed with those by standard method.This method is simple and rapid,and promises well to be adopted as an official assay method for determination of aspirin compound tablets