摘要
目的研究泽泻Alisma orientale的活性成分。方法采用硅胶柱色谱和HPLC制备色谱分离技术,根据理化性质和光谱数据鉴定化合物结构。结果从泽泻的醋酸乙酯萃取部分分离得到6个化合物,分别鉴定为11-羟基-13(17),25(27)-脱氢-原萜烷-3,24-二酮(1)、24-乙酰泽泻醇A(2)、24-乙酰泽泻醇F(3)、泽泻醇F(4)、泽泻醇G(5)、泽泻醇A(6)。结论化合物1为新化合物,命名为泽泻醇X。
Objective To study the chemical constituents from the rhizome of Alisma orientale.Methods Silica gel and HPLC column chromatography were used to purify the chemical constituents and their structures were elucidated on the basis of physicochemical properties and spectral data.Results Six compounds were isolated from ethyl acetate fraction of ethanol extract of A.orientale and identified as 11-hydroxy-13（17）,25（27）-dehydro-protostane-3,24-dione（1）,alisol A 24-acetate（2）,alisol F 24-acetate（3）,alisol F（4）,alisol G（5）,and alisol A（6）.Conclusion Compound 1 is a new compound named alisol X.
出处
《中草药》
CAS
CSCD
北大核心
2012年第5期841-843,共3页
Chinese Traditional and Herbal Drugs
基金
国家公益性中医药行业科研专项课题(200807039)
