摘要
目的研究仙鹤草Agrimoniae Herba的化学成分。方法利用硅胶柱色谱、大孔树脂柱色谱、Sephadex LH-20凝胶柱色谱进行反复分离纯化,根据化合物的理化性质和波谱数据鉴定其结构。结果从仙鹤草中分离得到19个化合物,分别鉴定为β-谷甾醇(1)、三十二烷醇(2)、三十一烷醇(3)、十九烷酸(4)、十六烷酸(5)、二十烷酸(6)、二十七烷酸(7)、胡萝卜苷(8)、委陵菜酸(9)、银锻苷(10)、芹菜素-7-O-β-D-吡喃葡萄糖醛酸甲酯(11)、芹菜素-7-O-β-D-吡喃葡萄糖醛酸丁酯(12)、仙鹤草酚B(13)、汉黄芩素(14)、芹菜素(15)、山柰酚(16)、乌苏酸(17)、槲皮素(18)、异槲皮苷(19)。结论化合物2~4、6、7、14均为首次从龙芽草属植物中获得。
Objective To investigate the chemical constituents of Agrimoniae Herba.Methods Repeated column chromatography with silical gel,maroporous resin column,and Sephadex LH-20 were used to isolate the chemical constituents,and their structures were elucidated on the physicochemical properties and basis of spectral data.Results Nineteen compounds were isolated and identified as β-sitosterol(1),dotriacontanol(2),hentriacontanol(3),nonadecanoic acid(4),palmitic acid(5),eicosanoic acid(6),heptacosanoic acid(7),daucosterol(8),tormentic acid(9),tiliroside(10),apigenin-7-O-methyl glucuronate(11),apigenin-7-O-butyl glucuronate(12),agrimophol B(13),wogonin(14),apigenin(15),kaempeferol(16),ursolic acid(17),quercetin(18),and isoquercitrin(19).Conclusion Compounds 2—4,6,7,and 14 are firstly obtained from the plants in Agrimonia L.
出处
《中草药》
CAS
CSCD
北大核心
2012年第5期851-855,共5页
Chinese Traditional and Herbal Drugs