恶性肿瘤患者体表面积计算方法的比较

Comparison of methods for calculating human body surface area in cancer patients

目的探讨不同体重指数(BMI)的恶性肿瘤患者体表面积的计算方法。方法对227例恶性肿瘤患者在住院当天、第2天和化疗前各测量1次空腹时的身高和实际体重,计算其平均值。按照不同BMI值(≤18.6kg/m2、18.6～23.9kg/m2、24～27.9kg/m2和≥28kg/m2)将患者分为消瘦组(17例)、正常体重组(107例)、超重组(82例)和肥胖组(21例);计算各组患者的实际和理想体表面积,比较两者间差异。结果正常体重组患者的实际和理想体表面积分别为1.590m2和1.584m2,差异无统计学意义(P>0.05);消瘦组患者的实际和理想体表面积分别为1.523m2和1.641m2(P<0.05);超重组患者的实际和理想体表面积分别为1.724m2和1.590m2(P<0.05);肥胖组患者的实际和理想体表面积分别为1.813m2和1.570m2(P<0.05)。结论不同BMI值患者的实际和理想体表面积有一定的差异,对于超重和肥胖的恶性肿瘤患者实施化疗建议根据理想体表面积计算化疗药物剂量,避免不必要的治疗风险。

Objective To extend the method for calculating human body surface area in cancer patients with different BMI ranges. Methods The actual body weight and the height of cancer patients were measured at admission, the second day and before chemotherapy to get the average value. The subjects were divided into magersucht group, normal quality group, overweight group and obesity group according to BMI（≤18. 6kg/m2, 18. 6-23.9kg/m2, 24-27. 9kg/m2 and ≥28kg/m2）. Ideal body weight, ideal surface area and actual surface area were formulated and analyzed. Results The actual body surface area and ideal body surface area were 1. 590m2 and 1. 584 m2 in normal quality group （P 〉0.05）. The actual body surface area and ideal body surface area were 1. 523m2 and 1. 641m2 ,1. 724m2 and 1. 590m2, 1. 813m2 and 1. 570m2 in magersucht group, overweight group and obesity group（ P 〈 O. 05 ）. Conclusion There are significant differences between actual body surface area and ideal body surface area of patients according to BMI classification. The ideal body surface area based on ideal body weight could get more precise drug dose and avoid otiose therapeu- tic risk.