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儿童1型糖尿病继发白内障1例回顾分析并文献复习 被引量:2

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摘要 目的探索儿童糖尿病性白内障可能的发病机制及预防控制方法。方法回顾性分析1例1型糖尿病患儿继发白内障的临床资料并进行相关文献复习。结果患者确诊1型糖尿病后8个月发生白内障,病程短,发展迅速,成熟快,严格控制血糖后行手术治疗获良好视力。结论多元醇通路是组织细胞内葡萄糖代谢的一个重要途径,晶状体内糖代谢紊乱而导致的高血糖状态,可激活多元醇通路,导致晶体内渗透压升高及氧化应激、蛋白质糖基化,促进糖尿病性白内障发生发展。良好的血糖管理是预防及延缓儿童糖尿病性白内障发生发展的关键;一旦发生,成熟后需通过手术治疗方可获良好视力。
出处 《中国医药指南》 2012年第12期279-280,共2页 Guide of China Medicine
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参考文献13

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