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卵巢囊性肿瘤伴附壁结节4例临床病理分析

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摘要 目的观察卵巢囊性肿瘤中附壁结节的临床表现、组织病理学和免疫表型特征,强调诊断标准并探讨病因机制及预后。方法分析4例卵巢囊性肿瘤中附壁结节的临床资料、组织学形态及其免疫学表型,并复习相关文献。结果 4例卵巢囊性肿瘤类型较为多样,其中2例为黏液及浆液性囊腺瘤,1例为浆液性囊腺瘤,1例为黏液性囊腺瘤。病例1为形态温和的梭形细胞附壁结节,免疫组织化学仅表达vimentin;病例2为良性梭形细胞附壁结节,梭形细胞核二端钝圆,VG染色呈黄色,vimentin、SMA、desmin阳性;病例3为恶性梭形细胞肉瘤样附壁结节,细胞呈蝌蚪状,胞质丰富红染,核分裂象易见,desmin、MyoD1阳性;病例4为类癌附壁结节,肿瘤细胞小,大小形态一致,呈腺样或巢状排列,CK、S-100、NSE、syn、CgA阳性。结论发生于卵巢非黏液性上皮性肿瘤中的附壁结节并非十分罕见,附壁结节具有广泛的病理形态图像谱,但由于恶性的附壁结节在囊内生长,且肉眼界限清楚,其生长方式决定了随着囊性肿瘤被早期切除后患者的预后较好。
作者 刘旭初
出处 《中国医药指南》 2012年第12期672-674,共3页 Guide of China Medicine
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