彩超水囊引导下A型肉毒毒素注射治疗面肌痉挛的临床疗效

Efficacy of Ultrasound and Water Capsule-guided Local Injection of Botulinum Toxin Type A Treatment on Patients with Facial Spasm

目的:探讨彩超水囊引导下肉毒毒素注射治疗面肌痉挛的疗效。方法:面肌痉挛患者96例,随机分为A、B组各48例,A组给予口服药物6个月,B组给予彩超水囊引导下局部注射A型肉毒毒素(BTX-A)。治疗前后分别采用Cohen、Acbert痉挛强度分级评估疗效,观察2组疗效、持续时间、显效率和治疗前后肌痉挛强度及变化情况。结果:A组治疗后肌痉挛强度变化无统计学差异,B组治疗后肌痉挛强度变化有显著性差异(P<0.01),且显效率高于A组(P<0.01)。结论:彩超水囊引导下BTX-A注射治疗能显著降低面肌痉挛的肌张力,且安全、简单易行。

Objective：To study the efficacy of ultrasound and water capsule-guided local injection of botulinum toxin type A（BTX-A） treatment on patients with facial spasm.Methods：Ninety-six cases of facial spasm were randomly divided into oral drug treatment group（A group）（48 cases） and ultrasound and water capsule-guided local injection of botulinum toxin type A treatment group（B group）（48 cases）.Cohen,Acbert spasms strength grade scores in each cases with facial spasm were recorded.Therapeutic effect,duration,significant efficiency and muscle spasms strength were compared before and 6 months after treatment.Results：The muscle spasms strength showed no significant change in A group after the treatment.However,the muscle spasms strength was decreased significantly in B group after treatment（P0.01）.Conclusion：Ultrasound and water capsule-guided local injection of botulinum toxin type A treatment is a safe,effective,and simple treatment for patients with facial spasm.