摘要
目的:探讨难治性癫痫(RE)的术前评估及手术治疗方案。方法:综合分析366例RE患者的临床病史、常规EEG、24hV-EEG、MRI、PET及神经心理评估结果,结合术中皮质电极描记(ECoG),选择适宜的手术方式。结果:术后随访发作控制满意201例(54.9%),发作明显改善96例(26.2%),发作控制良好39例(10.7%),发作控制较差或无改变30例(8.2%)。结论:对RE患者术前进行综合评估,制定合理的手术方案,可取得较好的治疗效果。
Objective：To explore the pre-surgical evaluation and surgical therapy strategy of intractable epilepsy cases.Methods：The clinical history,results of regular EEG,24-hours V-EEG,MRI,PET and neuropsychological evaluation were analyzed.The appropriate types of operation were determined in combination with intraoperative ECoG.Results：Among the follow-up analysis of 366 cases received surgical treatment,201 cases showed satisfied effect（54.9%）,96 patients had significant reduction of seizures（26.2%）,39 cases showed well-controlled seizures（10.7%）,and 30 cases experienced no improvement（8.2%）.Conclusion：Compositive pre-surgical evaluation and determination of appropriate operation strategy can help achieve a better therapeutic effect.
出处
《神经损伤与功能重建》
2012年第3期213-215,230,共4页
Neural Injury and Functional Reconstruction
基金
湖北省自然科学基金面上项目(No.2009CDB291
2011CDB560)
中国博士后科学基金特别项目(No.201003481)
关键词
难治性癫痫
术前评估
手术治疗
refractory epilepsy
pre-surgical evaluation
surgical therapy
