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Neuritin在神经发育、损伤和疾病中的变化及作用 被引量：4

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摘要 神经损伤和疾病（如老年痴呆、帕金森病等）的治疗一直是困扰人类的一大难题,其预后主要取决于神经受损后的再生修复能力。神经修复和再生受诸多因素的影响,其中神经营养因子起到了积极的促进作用。1993年Nedivi等^[2]通过构建谷氨酸类似物红藻氨酸盐（KA）激活大鼠海马齿状回cDNA文库，得到一系列与可塑性相关的候选基因（candidateplasticity-relatedgenes，CPGs）。
作者 曹文珞 许家军
机构地区 第二军医大学解剖学教研室
出处 《神经解剖学杂志》 CAS CSCD 北大核心 2012年第3期312-316,共5页 Chinese Journal of Neuroanatomy
关键词 NEURITIN 神经可塑性 神经损伤 神经系统疾病
分类号 R741 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献34

  • 1Fujino T, Lee WC, Nedivi E. Regulation of cpg15 by signaling pathways that mediate synaptic plasticity [ J ]. Mol Cell Neurosci, 2003, 24:538 -554.
  • 2Nedivi E, Hevroni D, Naot D, et al. Numerous candidate plasticity- related genes revealed by differential cDNA cloning [ J ]. Nature, 1993, 363:718 -722.
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二级参考文献38

  • 1唐娟,于娜,吴亮生,杨磊,仙玲玲,黄延红,张树军,黄瑾.人Neuritin在原核表达系统的构建及表达纯化[J].中国生物工程杂志,2006,26(4):46-50. 被引量：6
  • 2江基尧.弥漫性轴突损伤的概念和病理机制[J].中华神经外科杂志,2006,22(11):645-646. 被引量：27
  • 3王汉东.对弥漫性轴突损伤的认识[J].中华神经外科杂志,2006,22(11):647-648. 被引量：14
  • 4张树军,仙玲玲,于娜,巴鹏飞,徐芬,杨磊,黄瑾.Neuritin在毕赤酵母中的分泌表达与鉴定[J].农垦医学,2006,28(5):321-324. 被引量：1
  • 5李新丽,黄谨.神经营养因子Neuritin的生物学特性与神经再生[J].中国组织工程研究与临床康复,2007,11(19):3813-3816. 被引量：3
  • 6Dergham P, Ellezam B. Rho signaling pathway targeted to promote spinal cord repair. Neurosci, 2002, 22(15): 6570-6577.
  • 7Bulsara KR, Iskandar BJ, Villavicencio AT, et al. A new millennium for spinal cord regeneration: growth-associated genes. Spine, 2002, 27(17): 1946-1949.
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  • 10Karamoysoyli E, Burnand RC, TomLinson DR, et al. Neuritin mediates nerve growth factor-induced axonal regeneration and is deficient in experimental diabetic neuropathy. Diabetes, 2008, 57( 1): 181-189.

共引文献9

同被引文献45

  • 1唐娟,于娜,吴亮生,杨磊,仙玲玲,黄延红,张树军,黄瑾.人Neuritin在原核表达系统的构建及表达纯化[J].中国生物工程杂志,2006,26(4):46-50. 被引量：6
  • 2Nedivi E, Hevroni D, Naot D, et al. Numerous candidate plasticity related genes revealed by differential cDNA cloning [ J ] . Nature, 1993, 363 ( 6431 ) : 718-722.
  • 3Naeve GS, Ramakrishnan M, et al. Neuritin : A gene induced by neural activity and neurotrophins that promotes neuritogenesis [ J ] . Proc Natl Acad Sci, 1997, 94 ( 3 ) : 2648-2653.
  • 4Sato H, Fukutani Y： Yamamoto Y, et al. Thalamus-derived molecules promote survival and dendritic growth of developing cortical neurons [ J ]. J Neurosci, 2012, 31, 32 ( 44 ) : 15388-153402.
  • 5Fujino T, Wu Z, Lin WC, et al. Cpgl5 and Cpgl5-2 Constitute a family of activity-regulated ligands expressed differentially in the nervous system to promote neurite growth and neuronal survival [ J ]. J Comp Neurol, 2008, 507 ( 5 ) : 1831-1845.
  • 6Antypa M, Faux C, Eiehele G, et al. Differential gene expression in migratory streams of cortical interneurons [ J ]. Eur J Neurosei, 201l, 34 (10) : 1584-1594.
  • 7Zito A, Cartdli D, Cappelletti G, et al. Neuritin 1 promotes neuronal migration [ J ] . Eur J Neurosci, 2011, 34 ( 10 ) : 1584-1594.
  • 8Akten B, Kye MJ, Hao LT, et al. Interaction of survival of motor neuron ( SMN ) and HuD proteins with mRNA cpgl5 rescues motor neuron axonal deficits [J ] . Proc Natl Acad Sci USA, 2011, 108 : 10337-10342.
  • 9Fujino T, Lee WC, Ncdivi E. Regulation of cpgl5 by signaling pathways that mediate synaptic plasticity [ J ] . Mol Cell Neurosci, 2003, 24 ( 3 ) : 538-554.
  • 10Leslie JH, Nedivi E. Activity-regulated genes as mediators of neural circuit plasticity [ J ] . Prog Neurobiol, 2011, 94 ( 3 ) : 223-237.

引证文献4

二级引证文献10

神经解剖学杂志
2012年 第3期

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