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正确认识与合理使用质子泵抑制剂 被引量:28

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摘要 质子泵抑制剂(proton pump inhibitors,PPIs)的研发与应用开创了药物治疗各种酸相关疾病如消化性溃疡、胃食管反流病(GERD)以及佐林格-埃利森综合征(Zollinger-Ellison syndrome)的新时代^[1]。
作者 孙忠实
机构地区 北京
出处 《中华内科杂志》 CAS CSCD 北大核心 2012年第6期417-419,共3页 Chinese Journal of Internal Medicine
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参考文献15

  • 1FDA. Possible increased risk of bone fractures with certain antacid drugs [ EB/OL ]. [ 2010-05-25 ]. http://www, fda. gov/ downloads/ForConsumers/ConsumerUpdates/UCM213307, pdf.
  • 2McDonagh MS, Carso S, Thakurta S. Drug Class Review: Proton Pump Inhibitors. Final Report Update5 [ EB/OL ]. ( 20094 ) [ 2012-3-15 ]. http ://derp. ohsu. edu/final/PPI_final_evidence% 20tables_update% 205_unshaded 09 MAY. pdf.
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  • 5FDA. Information for Healthcare Professionals: Update to the labeling of Clopidogrel Bisulfate (marketed as Plavix ) to alert heahhcare professionals about a drug interaction with omeprazole ( marketed as Prilosec and Prilosec OTC ) [ EB/OL ]. ( 2009-11 - 17 ) [ 2012-03-15 1. http://www, fda. gov/Drugs/DrugSafety/ PostmarkPatientsandProviders/DrugSafetylnformationforHeathcareProfessionals/ucm190787. htm.
  • 6Furuta T, Shirai N, Takashima M, et al. Effect of genotypic differences in CYP2C19 on cure rates for Helicobacter pylori infection by triple therapy with a proton pump inhibitor, amoxicillin, and clarithromycin. Clin Pharmacol Ther, 2001,69 : 158-168.
  • 7Ho PM, Maddox TM, Wang L, et al. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA, 2009,301:937-944.
  • 8FDA reminder to avoid concomitant use of Plavix ( clopidogrel ) and omeprazole [ EB/OL ]. [ 2012-03-15 ]. http ://www. fda. gov/ Drugs/DrugSafety/ucm231161. htm.
  • 9Abraham NS, Hlatky MA, Antman EM, et al. ACCF/ACG/AHA 2010 Expert Consensus Document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use : a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. Circulation, 2010, 122: 2619-2633.
  • 10Marcus GM, Smith LM, Scheinman MM, et al. Proton Pump Inhibitors are Associated with Focal Arrhythmias. J Innov in Card Rhythm Manag, 2010,1:85-89.

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